2-Chloroadenosine

CAS 146-77-0C10H12ClN5O4Biochemicals & Reagents

2-Chloroadenosine (CAS: 146-77-0; Formula: C10H12ClN5O4) is a synthetic nucleoside analogue. With a molecular weight of 301.69 g/mol, it serves as a valuable biochemical reagent. Its primary applications lie in research, particularly within cell biology and neuroscience, where it is utilized for its agonist properties related to purinergic receptors. This compound is essential for studies investigating cellular signalling pathways and neurotransmission.

IUPAC: 2-CADO,6-Amino-2-chloropurine riboside
Synonyms: 2-CADO6-Amino-2-chloropurine riboside

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2-Chloroadenosine (C10H12ClN5O4) — chemical structure, CAS 146-77-0; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBioactive Small MoleculesBiochemicals and ReagentsC-CHCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscienceNeurotransmission

01 /Applications

Neuroscience Research

2-Chloroadenosine acts as an agonist for P2 nucleotide receptors, making it useful for studying neuronal function and neurotransmission. Researchers use it to probe receptor mechanisms and signalling cascades in the nervous system.

Cellular Signalling Studies

This compound is employed in biochemical research to investigate cellular responses mediated by adenosine receptors. It aids in understanding signal transduction pathways in various cell types.

GPCR Modulator Research

As a modulator of G protein-coupled receptors (GPCRs), 2-Chloroadenosine is a tool for exploring the complex interactions within these vital cellular signalling systems. It is particularly relevant for studies involving purinergic receptors.

02 /Properties

Molecular weight	301.69
Empirical formula	C10H12ClN5O4

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

146-77-0

MDL number

MFCD00005734

Beilstein registry

43957

05 /Additional specifications

Gene Information	human ... ADORA1(134), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2-Chloroadenosine used for?

2-Chloroadenosine (CAS: 146-77-0) is used as a research chemical, primarily as an agonist for P2 nucleotide receptors, aiding in studies of neuroscience, cell signalling, and GPCR modulation.

What is the CAS number and formula for 2-Chloroadenosine?

The CAS number for 2-Chloroadenosine is 146-77-0, and its molecular formula is C10H12ClN5O4.

What grade and purity does Tech Serve Solutions supply for 2-Chloroadenosine?

Tech Serve Solutions supplies 2-Chloroadenosine as a research grade chemical. We do not represent it as USP, BP, EP, or other pharmacopoeial grades. Please refer to the product specifications for detailed purity information, which can be provided upon request.

What are the safety and handling recommendations for 2-Chloroadenosine?

2-Chloroadenosine should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information.

How is 2-Chloroadenosine packed, shipped, and exported?

2-Chloroadenosine is carefully packed to maintain its integrity during transit and is available for global export. Specific packaging details depend on the quantity and destination, adhering to all relevant shipping regulations.

How can I request a quote or sample of 2-Chloroadenosine?

To request a quote or a sample of 2-Chloroadenosine, please contact our sales team through the website or by direct inquiry, providing your specific requirements.