(R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol
(R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol (CAS: 152491-85-5) is a protected amino alcohol derivative. With a molecular weight of 305.49 g/mol, this chiral compound features tert-butyloxycarbonyl (Boc) protection on the amine and tert-butyldimethylsilyl (TBS) protection on the hydroxyl group. It is primarily utilised in organic synthesis, particularly in peptide chemistry and the development of complex chiral molecules, serving as a valuable building block.
![(R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol ((CH3)3CSi(CH3)2OCH2CH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 152491-85-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F152491-85-5.png&w=3840&q=75)
Peptide Synthesis
This protected serinol derivative is employed as a chiral building block in solid-phase or solution-phase peptide synthesis. Its functional groups allow for controlled coupling reactions in the construction of peptide chains.
Organic Synthesis
The compound serves as a versatile intermediate in the synthesis of various organic molecules. The orthogonal protecting groups enable selective deprotection and further functionalization in multi-step synthetic pathways.
Chiral Building Block
As a stereochemically defined molecule, it is instrumental in asymmetric synthesis, contributing to the creation of enantiomerically pure target compounds in medicinal chemistry and materials science.
Research and Development
Utilised in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chemical entities with potential biological activity.
| Molecular weight | 305.49 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2OCH2CH[NHCO2C(CH3)3]CH2OH |
| Assay | 97% |
| Optical activity | [α]20/D +17°, c = 1 in chloroform |
| Melting point | 32-37 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 115 °C / 239 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol primarily used for?
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This compound is primarily used as a chiral building block in organic synthesis, particularly in peptide chemistry and the development of complex molecules.
What are the CAS number and molecular formula for this product?
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The CAS number is 152491-85-5. The linear formula is (CH3)3CSi(CH3)2OCH2CH[NHCO2C(CH3)3]CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol be handled?
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According to GHS, this compound is a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is this chemical packed and shipped?
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This chemical is carefully packed according to industry standards to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or a quote for this product?
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Please contact our sales team directly via our website or by phone to request a sample or obtain a quotation for (R)-(+)-N-(tert-Butoxycarbonyl)-O-(tert-butyldimethylsilyl)serinol.
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