O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol
O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol (CAS 756525-99-2), a heterobifunctional PEGylation reagent, has a molecular weight of 513.50 g/mol and the empirical formula C22H31N3O11. This compound facilitates the conjugation of molecules through its maleimide and NHS ester functional groups, making it valuable in chemical biology and synthesis for creating bioconjugates and crosslinked structures.
- IUPAC
- N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide,monodisperse Mal-PEG4-NHS-ester
![O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol (C22H31N3O11) — chemical structure, CAS 756525-99-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F756525-99-2.png&w=3840&q=75)
Bioconjugation
Utilised to covalently link biomolecules, such as proteins, peptides, or antibodies, to other molecules or surfaces. The maleimide group reacts with thiols, and the NHS ester reacts with primary amines.
Surface Modification
Enables the functionalisation of surfaces with specific chemical groups, improving biocompatibility or enabling further immobilisation of biological entities. It is useful in the development of biosensors and diagnostic devices.
Crosslinking Agent
Acts as a flexible linker to join different molecular entities together, creating more complex structures. This is important in areas like hydrogel formation or the creation of antibody-drug conjugates.
Drug Delivery Systems
Can be incorporated into the design of targeted drug delivery vehicles, facilitating the attachment of therapeutic agents to targeting ligands or modifying the pharmacokinetic properties of drugs.
| Molecular weight | 513.50 |
|---|---|
| Empirical formula | C22H31N3O11 |
| Assay | ≥90% (NMR) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol used for?
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This compound is a heterobifunctional PEGylation reagent primarily used for bioconjugation and crosslinking in chemical biology and synthesis. It facilitates the linkage of molecules with thiol and amine groups.
What are the CAS number and formula for this product?
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The CAS number is 756525-99-2 and the empirical formula is C22H31N3O11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥90% (NMR). TSS does not represent this product as USP, BP, or EP grade.
How should O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C.
Is this product a controlled substance?
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There is no indication in the provided data that this compound is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details can be provided upon request.
How can I request a sample or quote?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a sample or a quote for this product.
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