3′,5′-Dimethoxyacetophenone
3′,5′-Dimethoxyacetophenone (CAS 39151-19-4) is an aromatic ketone with the molecular formula C10H12O3 and a molecular weight of 180.20 g/mol. This compound serves as a valuable building block in organic synthesis. It has been utilised as a starting reagent in the creation of various heterocyclic compounds and substituted phenyl derivatives, making it a key intermediate for researchers and manufacturers in the fine chemical and pharmaceutical sectors.
- Synonyms
- (CH3O)2C6H3COCH3

Synthesis of Indazole Derivatives
3′,5′-Dimethoxyacetophenone has been employed as a key starting material in the synthesis of 5,7-dimethoxy-3-methylindazole, contributing to the development of novel heterocyclic structures.
Preparation of Chiral Esters
This acetophenone derivative is used in the synthesis of specific chiral compounds, such as (R)-(+)-1-(3,5-dimethoxyphenyl)ethyl acetate, which are important in stereoselective synthesis.
Organic Building Block
As a versatile ketone, it functions as a fundamental building block in various chemical synthesis pathways, enabling the construction of more complex organic molecules.
| Molecular weight | 180.20 |
|---|---|
| Linear formula | (CH3O)2C6H3COCH3 |
| Assay | 97% |
| Boiling point | 290-291 °C(lit.) |
| Refractive index | n20/D 1.543(lit.) |
| Application | 3′,5′-Dimethoxyacetophenone was used as starting reagent in the synthesis of 5,7-dimethoxy-3-methylindazole1. It was used in the synthesis of (R)-(+)-1-(3,5-dimethoxyphenyl)ethyl acetate-ether-1802. |
| Melting point | 33-34 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3′,5′-Dimethoxyacetophenone used for?
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3′,5′-Dimethoxyacetophenone is used as a starting reagent in organic synthesis, particularly in the preparation of indazole derivatives and chiral esters.
What are the CAS number and molecular formula of 3′,5′-Dimethoxyacetophenone?
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The CAS number for 3′,5′-Dimethoxyacetophenone is 39151-19-4, and its molecular formula is (CH3O)2C6H3COCH3.
What grade and purity does Tech Serve Solutions supply for 3′,5′-Dimethoxyacetophenone?
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Tech Serve Solutions supplies 3′,5′-Dimethoxyacetophenone with a minimum assay of 97%. This product is intended for laboratory and research purposes, and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3′,5′-Dimethoxyacetophenone be handled safely?
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Handling of 3′,5′-Dimethoxyacetophenone requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. The compound has a flash point of 113 °C (235.4 °F) and is classified under WGK Germany 3.
Is 3′,5′-Dimethoxyacetophenone exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3′,5′-Dimethoxyacetophenone, adhering to international shipping standards.
How can I request a quote or sample for 3′,5′-Dimethoxyacetophenone?
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To request a quote or a sample of 3′,5′-Dimethoxyacetophenone, please contact our sales department through the website or by calling our office.
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