tert-Butyl 1-indolecarboxylate
Tert-Butyl 1-indolecarboxylate (CAS: 75400-67-8, Formula: C13H15NO2, Molar Mass: 217.26 g/mol) is a key indole derivative used in organic synthesis. Supplied by Tech Serve Solutions, this compound serves as a valuable building block for the preparation of various biologically active molecules and in cross-coupling reactions. Its precise chemical nature makes it an indispensable reagent for researchers and chemists in diverse fields.
- IUPAC
- 1-(tert-Butoxycarbonyl)indole,1-Indolecarboxylic acid tert-butyl ester,N-tert-Butoxycarbonylindole,N-Butyloxycarbonylindole
- Synonyms
- 1-(tert-Butoxycarbonyl)indole1-Indolecarboxylic acid tert-butyl esterN-tert-ButoxycarbonylindoleN-Butyloxycarbonylindole
Synthesis of Plant-Growth Inhibitors
Tert-Butyl 1-indolecarboxylate is employed as a reactant in the preparation of potent plant-growth inhibitors, contributing to advancements in agricultural science and research.
Development of Cannabinoid Receptor Ligands
This indole derivative is utilized in the synthesis of cannabinoid CB2 receptor ligands, supporting research into potential therapeutic agents.
Preparation of GSK-3β Inhibitors
It serves as a reactant for the synthesis of analogues of isomeridianin G and their evaluation as inhibitors of GSK-3β, a target in various disease research areas.
Synthesis of Antileishmanial Agents
Tert-Butyl 1-indolecarboxylate is a precursor in the synthesis of antileishmanial agents, aiding the development of new treatments for leishmaniasis.
Cross-Coupling Reactions
The compound is a reactant in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds in complex molecule synthesis.
| Molecular weight | 217.26 |
|---|---|
| Empirical formula | C13H15NO2 |
| Assay | 97% |
| Boiling point | 201 °C(lit.) |
| Density | 1.07 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.543(lit.) |
| Application | Reactant for preparation of:• Potent plant-growth inhibitors1• Cannabinoid CB2 receptor ligands2• Analogues of isomeridianin G and evaluation as GSK-3β inhibitors3• Inhibitor of the Yersinia pestis salicylate adenylation domain YbtE4• Cholecystokinin-2 receptor antagonists5• Antileishmanial agents6• Reactant for:• Palladium-catalyzed Suzuki-Miyaura cross coupling reactions7• Friedel-Crafts alkylation reactions8 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tert-Butyl 1-indolecarboxylate used for?
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Tert-Butyl 1-indolecarboxylate is used as a reactant for the preparation of potent plant-growth inhibitors, cannabinoid CB2 receptor ligands, GSK-3β inhibitors, antileishmanial agents, and in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions.
What is the CAS number and formula for Tert-Butyl 1-indolecarboxylate?
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The CAS number is 75400-67-8 and the empirical formula (Hill Notation) is C13H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tert-Butyl 1-indolecarboxylate with an assay of 97%. This product is suitable for research and technical applications. Tech Serve Solutions does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Tert-Butyl 1-indolecarboxylate?
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Handling Tert-Butyl 1-indolecarboxylate requires appropriate personal protective equipment, including eyeshields, gloves, and a half-mask respirator (EU or US). It has a flash point of 71 °C (159.8 °F) and is classified under NA 1993 / PGIII. Always consult the Safety Data Sheet (SDS) before use.
How is Tert-Butyl 1-indolecarboxylate shipped and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures that Tert-Butyl 1-indolecarboxylate is packed and exported in compliance with all relevant international shipping regulations for chemicals.
How can I request a sample or quote for Tert-Butyl 1-indolecarboxylate?
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To request a sample or a quotation for Tert-Butyl 1-indolecarboxylate, please contact our sales team through the website or by phone. Our team will be pleased to assist you with your specific requirements.
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