tert-Butyl (tert-butyldimethylsilyl)glyoxylate
tert-Butyl (tert-butyldimethylsilyl)glyoxylate (CAS: 852447-17-7; C12H24O3Si) is a specialised organic building block with a molecular weight of 244.40 g/mol. This compound serves as a versatile intermediate in organic synthesis, particularly in the construction of complex molecules. It finds utility in research and development laboratories for applications requiring precise chemical modifications and is exported globally by Tech Serve Solutions.

Organic Synthesis Intermediate
This glyoxylate derivative acts as a key building block in multi-step organic synthesis. Its protected form allows for selective reactions, facilitating the creation of intricate molecular architectures in academic and industrial research settings.
Research and Development
Utilised in R&D laboratories for exploring novel synthetic pathways and developing new chemical entities. Its specific structure makes it valuable for introducing protected glyoxylate functionalities into target molecules.
Chemical Manufacturing
Serves as an intermediate in the fine chemical and pharmaceutical sectors, contributing to the synthesis of more complex active pharmaceutical ingredients (APIs) or advanced materials.
| Molecular weight | 244.40 |
|---|---|
| Empirical formula | C12H24O3Si |
| Assay | 97% |
| Density | 0.920 g/mL at 25 °C |
| Refractive index | n20/D 1.440 |
| Application | Learn More at the Professor and Product Portal of Professor Jeffrey S. Johnson. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 88 °C / 190.4 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyl (tert-butyldimethylsilyl)glyoxylate used for?
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tert-Butyl (tert-butyldimethylsilyl)glyoxylate is primarily used as a versatile intermediate in organic synthesis and in research and development laboratories for constructing complex molecules and exploring novel synthetic pathways.
What are the CAS number and molecular formula?
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The CAS number for tert-Butyl (tert-butyldimethylsilyl)glyoxylate is 852447-17-7, and its molecular formula is C12H24O3Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies tert-Butyl (tert-butyldimethylsilyl)glyoxylate with a minimum assay of 97%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
How should tert-Butyl (tert-butyldimethylsilyl)glyoxylate be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing vapours or mist. P261, P305 + P351 + P338 are key precautionary statements.
Is this chemical a controlled substance?
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Based on the provided data, tert-Butyl (tert-butyldimethylsilyl)glyoxylate is not indicated as a controlled substance.
How is this chemical packed and shipped?
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The product is shipped according to regulations, with appropriate packaging for hazardous materials (NA 1993 / PGIII). Tech Serve Solutions is a global supplier and exporter, ensuring compliance with international shipping standards.
How can I request a sample or quote?
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To request a sample or a quote for tert-Butyl (tert-butyldimethylsilyl)glyoxylate, please contact our sales department via the website or by phone. Our team will be pleased to assist you with your inquiry.
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