tert-Butyl (S)-2-pyrrolidone-5-carboxylate
tert-Butyl (S)-2-pyrrolidone-5-carboxylate (CAS: 35418-16-7; C9H15NO3) is a chiral building block with a molecular weight of 185.22 g/mol. It serves as a key intermediate in asymmetric synthesis and the construction of heterocyclic compounds. This compound is essential for researchers and manufacturers involved in developing complex organic molecules, particularly within the pharmaceutical and fine chemical industries.
- IUPAC
- tert-Butyl (S)-5-oxo-2-pyrrolidinecarboxylate,tert-Butyl 5-oxo-L-prolinate,tert-Butyl L-pyroglutamate
- Synonyms
- tert-Butyl (S)-5-oxo-2-pyrrolidinecarboxylatetert-Butyl 5-oxo-L-prolinatetert-Butyl L-pyroglutamate

Chiral Synthesis Intermediate
Utilised as a precursor in the stereoselective synthesis of complex chiral molecules. Its defined stereochemistry is crucial for creating enantiomerically pure compounds, vital in drug discovery and development.
Heterocyclic Compound Synthesis
A valuable building block for constructing diverse heterocyclic scaffolds. It facilitates the incorporation of the pyrrolidone ring system into larger molecular architectures, relevant for medicinal chemistry.
Pharmaceutical Research
Employed in the research and development of novel pharmaceutical agents. Its structure lends itself to the synthesis of biologically active compounds with potential therapeutic applications.
| Molecular weight | 185.22 |
|---|---|
| Empirical formula | C9H15NO3 |
| Assay | ≥98% (GC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyl (S)-2-pyrrolidone-5-carboxylate used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and for the construction of heterocyclic compounds, particularly in pharmaceutical research and fine chemical synthesis.
What are the CAS number and chemical formula?
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The CAS number is 35418-16-7 and the chemical formula is C9H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies tert-Butyl (S)-2-pyrrolidone-5-carboxylate with a purity of ≥98% (GC). This product is supplied for research and manufacturing purposes; TSS does not represent it as USP, BP, or EP grade.
How should tert-Butyl (S)-2-pyrrolidone-5-carboxylate be handled safely?
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This compound is classified as a skin and eye irritant (H315-H319). When handling, wear appropriate personal protective equipment including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do.
Can you provide synonyms for this chemical?
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Synonyms include tert-Butyl (S)-5-oxo-2-pyrrolidinecarboxylate, tert-Butyl 5-oxo-L-prolinate, and tert-Butyl L-pyroglutamate.
How is this chemical packed and shipped?
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This chemical is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote?
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To request a sample or obtain a quote for tert-Butyl (S)-2-pyrrolidone-5-carboxylate, please contact our sales team via the website or designated contact channels.
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