Topotecan hydrochloride hydrate
Topotecan hydrochloride hydrate (CAS 123948-87-8 (free base)), molecular formula C23H23N3O5 · xHCl · yH2O, is a high-purity chemical supplied by Tech Serve Solutions for cell biology applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- 9-[(dimethylamino)methyl]-10-hydroxy-(20S)-camptothecin hydrochloride hydrate,NSC-609669 hydrochloride hydrate,SKF-104864A hydrochloride hydrate,hycamptamine hydrochloride hydrate
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| Molecular weight | 421.45 (anhydrous free base basis) |
|---|---|
| Empirical formula | C23H23N3O5 · xHCl · yH2O |
| Assay | ≥98% (HPLC and enzymatic) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | −20°C |
| Application | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions1. It has also been used for in vitro apoptosis assays in PA317 cells2. |

Hazard statements
- H341Suspected of causing genetic defects
Precautionary statements
- P281Use personal protective equipment as required
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 46-48 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Topotecan hydrochloride hydrate?
+
Topotecan hydrochloride hydrate (CAS 123948-87-8 (free base)), molecular formula C23H23N3O5 · xHCl · yH2O, is a high-purity chemical supplied by Tech Serve Solutions for cell biology applications, to USP, BP and EP standards.
What grades of Topotecan hydrochloride hydrate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Topotecan hydrochloride hydrate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Topotecan hydrochloride hydrate?
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Topotecan hydrochloride hydrate has CAS number 123948-87-8 (free base) and molecular formula C23H23N3O5 · xHCl · yH2O. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Topotecan hydrochloride hydrate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Topotecan hydrochloride hydrate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Topotecan hydrochloride hydrate be stored?
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Store Topotecan hydrochloride hydrate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Topotecan hydrochloride hydrate used for?
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Topotecan hydrochloride hydrate is used in cell biology applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Topotecan hydrochloride hydrate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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