Ethyl trimethylsilyl malonate
Ethyl trimethylsilyl malonate (CAS: 18457-03-9), with the linear formula H₃CCH₂OCOCH₂COOSi(CH₃)₃ and a molecular weight of 204.30 g/mol, is a versatile organosilicon compound. It functions as a valuable building block in organic synthesis. Its chemical structure allows for diverse reactions, making it a useful reagent in the development of novel compounds and materials within academic and industrial research settings.

Organic Synthesis Reagent
Ethyl trimethylsilyl malonate serves as a key intermediate in various organic transformations. It is employed in the construction of complex molecular architectures, facilitating carbon-carbon bond formation and other synthetic strategies.
Building Block for Specialty Chemicals
This compound acts as a foundational element for the synthesis of more intricate organic molecules. Its unique silyl ester functionality enables selective reactions and protection/deprotection strategies.
Research and Development
Utilised in laboratories for exploring new synthetic routes and developing novel compounds, Ethyl trimethylsilyl malonate is instrumental in advancing chemical research across diverse fields.
| Molecular weight | 204.30 |
|---|---|
| Linear formula | H3CCH2OCOCH2COOSi(CH3)3 |
| Assay | 97% |
| Boiling point | 75 °C/0.5 mmHg(lit.) |
| Density | 1 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.) |
| Storage temperature | 2-8°C |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 50 °C / 122 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl trimethylsilyl malonate used for?
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Ethyl trimethylsilyl malonate is primarily used as a building block and reagent in organic synthesis for the development of complex molecules and specialty chemicals in research and industrial applications.
What is the CAS number and formula for Ethyl trimethylsilyl malonate?
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The CAS number is 18457-03-9, and its linear formula is H₃CCH₂OCOCH₂COOSi(CH₃)₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl trimethylsilyl malonate with a minimum assay of 97%. This product is suitable for research and general laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should Ethyl trimethylsilyl malonate be handled safely?
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Ethyl trimethylsilyl malonate is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation. Store away from heat and ignition sources.
Is Ethyl trimethylsilyl malonate a controlled substance?
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Based on the provided data, Ethyl trimethylsilyl malonate is not listed as a controlled substance.
How is this chemical packed and exported?
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Products are carefully packed according to international shipping regulations for hazardous materials and exported globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or a sample of Ethyl trimethylsilyl malonate, please contact our sales team via the website or your dedicated account manager.
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