Gly-Phe
Glycyl-L-phenylalanine (CAS 3321-03-7) is a dipeptide composed of glycine and phenylalanine. With a molecular weight of 222.24 g/mol, this compound finds utility in various chemical and biological research applications. It is particularly relevant in the fields of peptide chemistry and chemical synthesis, serving as a building block or research tool for developing novel molecules and understanding biochemical pathways.
- IUPAC
- Glycyl-L-phenylalanine
- Synonyms
- Glycyl-L-phenylalanine

Peptide Synthesis
Gly-Phe serves as a dipeptide building block in the synthesis of larger peptides and peptidomimetics. Its defined structure facilitates controlled chain elongation in complex peptide sequences.
Chemical Biology Research
This compound is used in chemical biology to study enzyme activity, protein-ligand interactions, and to develop novel biochemical probes. Its specific sequence can mimic or inhibit biological processes.
Amino Acid Derivative Studies
As an amino acid derivative, Gly-Phe is valuable for researchers investigating the properties and reactivity of modified peptides. It can be used in structure-activity relationship studies.
Chemical Synthesis Intermediate
Gly-Phe can function as an intermediate in the synthesis of complex organic molecules, particularly those with biological relevance or pharmaceutical applications.
| Molecular weight | 222.24 |
|---|---|
| Linear formula | NH2CH2CONHCH(COOH)CH2C6H5 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D +42±2°, c = 2% in H2O |
| Storage temperature | −20°C |
| Melting point | ~264 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Gly-Phe used for?
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Gly-Phe is primarily used in peptide synthesis, chemical biology research, and as an intermediate in chemical synthesis. It serves as a dipeptide building block and a tool for studying biochemical pathways and molecular interactions.
What are the CAS number and formula for Gly-Phe?
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The CAS number for Gly-Phe is 3321-03-7. The linear formula is NH₂CH₂CONHCH(COOH)CH₂C₆H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Gly-Phe with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Gly-Phe be handled and stored?
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Gly-Phe should be stored at -20°C. When handling, it is recommended to use safety measures such as eyeshields and gloves, and a P1 (EN143) or N95 (US) respirator filter. The compound has a GHS hazard classification of WGK 2 in Germany.
Is Gly-Phe a scheduled or controlled substance?
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Based on the provided data, Gly-Phe is not indicated as a scheduled or controlled substance.
How is Gly-Phe packed and exported?
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Tech Serve Solutions expertly packs and exports chemicals worldwide, ensuring appropriate handling and shipping procedures are followed to maintain product integrity and comply with international regulations.
How can I request a sample or quote for Gly-Phe?
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To request a sample or a quote for Gly-Phe, please contact our sales team through the website or by phone, providing your contact details and required quantity.
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