Tolvaptan
Tolvaptan (CAS: 150683-30-0), with the molecular formula C26H25ClN2O3 and a molecular weight of 448.94 g/mol, is a selective vasopressin V2-receptor antagonist. This compound is primarily utilised in research settings for its antagonist properties. Available as a white to tan powder, Tolvaptan is offered with a purity of ≥98% by HPLC. It is stored under refrigerated conditions (2-8°C) to maintain its integrity.
- IUPAC
- N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide,OPC 41061

V2-Receptor Antagonist Research
Tolvaptan functions as a selective antagonist of the vasopressin V2 receptor. It has been employed in preclinical studies to investigate the physiological effects of V2 receptor blockade, including its impact on fluid balance and potential therapeutic applications in conditions like hypertension.
Hypertension Studies
Research has utilised Tolvaptan to explore its effects on hypertension in animal models. By antagonising the V2 receptor, it helps scientists understand the role of vasopressin in blood pressure regulation and explore potential interventions.
Cell Biology Research
As a compound with known biological activity, Tolvaptan is relevant in cell biology research, particularly in studies involving cell signaling pathways related to hormone receptors and ion transport.
| Molecular weight | 448.94 |
|---|---|
| Empirical formula | C26H25ClN2O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥15 mg/mL |
| Storage temperature | 2-8°C |
| Application | Tolvaptan has been used as a V2-selective antagonist for studying its effect on hypertension in mice1. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tolvaptan used for?
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Tolvaptan is used as a V2-selective antagonist in research, notably for studying its effects on hypertension in mice and in cell biology research related to hormone receptors.
What is the CAS number and molecular formula for Tolvaptan?
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The CAS number for Tolvaptan is 150683-30-0, and its molecular formula is C26H25ClN2O3.
What grade and purity does Tech Serve Solutions supply for Tolvaptan?
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Tech Serve Solutions supplies Tolvaptan with a purity of ≥98% (HPLC). This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should Tolvaptan be handled and stored?
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Tolvaptan is classified under WGK 2 in Germany, indicating it is hazardous to water. It should be handled with appropriate laboratory precautions and stored at 2-8°C.
Is Tolvaptan a controlled substance?
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The provided data does not indicate that Tolvaptan is a controlled substance.
How is Tolvaptan packed, shipped, and exported?
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Tolvaptan is supplied as a white to tan powder. As a global supplier, Tech Serve Solutions adheres to all regulations for the packing, shipping, and export of fine chemicals.
How can I request a sample or quote for Tolvaptan?
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To request a sample or quote for Tolvaptan, please contact our sales team through the website or by phone, providing the product name and CAS number.
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