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tert-Butyl 12-amino-4,7,10-trioxadodecanoate

CAS 252881-74-6C13H27NO5Chemical Synthesis

Tert-Butyl 12-amino-4,7,10-trioxadodecanoate (CAS: 252881-74-6), with a molecular formula of C13H27NO5 and a molecular weight of 277.36 g/mol, is a functionalized oligoethylene glycol derivative. It serves as a valuable building block in chemical synthesis and chemical biology. This compound is commonly employed in the development of PEGylated molecules and in various research applications requiring polyethylene glycol functionalities.

IUPAC
tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate
Synonyms
252881-74-6, C13H27NO5, tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate
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tert-Butyl 12-amino-4,7,10-trioxadodecanoate (C13H27NO5) — chemical structure, CAS 252881-74-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical BiologyChemical SynthesisPEGylation
01 /Applications

Chemical Synthesis

This compound acts as a versatile intermediate in organic synthesis. Its amino and ester functionalities, along with the oligoethylene glycol chain, allow for diverse chemical modifications and conjugations.

PEGylation

Utilised for introducing polyethylene glycol (PEG) chains onto other molecules, such as proteins or small molecules, to improve solubility, stability, and pharmacokinetic profiles in drug development.

Chemical Biology Research

Serves as a reagent in chemical biology for creating modified biomolecules or probes. Its structure is useful for studying biological processes or for targeted delivery systems.

Functionalized Oligoethylene Glycols

As a derivative of oligoethylene glycol, it can be used to create specialised reagents with tailored properties for various biochemical and material science applications.

02 /Properties
Molecular weight277.36
Empirical formulaC13H27NO5
Assay≥80% (T)
Gradetechnical
Storage temperature−20°C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point169 °C / 336.2 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
252881-74-6
MDL number
MFCD06201017
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is tert-Butyl 12-amino-4,7,10-trioxadodecanoate used for?

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This compound is used in chemical synthesis, for PEGylation applications, and in chemical biology research as a functionalized oligoethylene glycol building block.

What are the CAS number and molecular formula?

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The CAS number is 252881-74-6 and the empirical formula (Hill notation) is C13H27NO5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical in technical grade with an assay of ≥80% (T). We do not represent this product as USP, BP, or EP grade.

How should tert-Butyl 12-amino-4,7,10-trioxadodecanoate be handled safely?

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This compound is a Warning substance (GHS07) with hazards H315, H319, and H335. It causes skin irritation, serious eye irritation, and may cause respiratory irritation. Use appropriate personal protective equipment, including eyeshields and suitable gloves, and ensure adequate ventilation. Avoid breathing vapours or dust.

How is this chemical packed and shipped?

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Products are packed according to international shipping regulations. Please contact us for specific export or bulk quantity details.

How can I request a sample or quote?

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To request a sample or a quote, please contact our sales department via the website or by phone, providing your specific requirements.

Need tert-Butyl 12-amino-4,7,10-trioxadodecanoate in a specific grade or volume?