3,5-Dimethylbenzenesulfonyl chloride
3,5-Dimethylbenzenesulfonyl chloride (CAS 2905-27-3) is an organic compound featuring a sulfonyl chloride functional group attached to a 3,5-dimethylphenyl ring. With a molecular weight of 204.67 g/mol, it serves as a valuable intermediate and building block in organic synthesis. Its reactivity makes it useful for introducing the 3,5-dimethylbenzenesulfonyl moiety into various molecules, finding applications in the development of novel chemical entities.
- Synonyms
- (CH3)2C6H3SO2Cl

Organic Synthesis Intermediate
Acts as a key building block for constructing more complex organic molecules. It is employed in reactions to introduce the 3,5-dimethylbenzenesulfonyl group, useful in the synthesis of pharmaceuticals and agrochemicals.
Research and Development
Utilised in laboratory settings for exploring new synthetic routes and developing novel compounds. Its specific structure allows for targeted modifications in research chemistry projects.
Sulfonamide Formation
Reacts with amines to form sulfonamides, a class of compounds with diverse biological activities and applications in medicinal chemistry.
| Molecular weight | 204.67 |
|---|---|
| Linear formula | (CH3)2C6H3SO2Cl |
| Assay | 97% |
| Melting point | 90-94 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dimethylbenzenesulfonyl chloride used for?
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3,5-Dimethylbenzenesulfonyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for introducing the 3,5-dimethylbenzenesulfonyl moiety into other molecules. It is valuable in research and development for creating new chemical entities, including sulfonamides.
What is the CAS number and chemical formula for 3,5-Dimethylbenzenesulfonyl chloride?
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The CAS number is 2905-27-3. The linear formula is (CH3)2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dimethylbenzenesulfonyl chloride with an assay of 97%. This product is typically supplied for research and industrial use and is not represented as meeting USP, BP, or EP pharmacopoeia standards.
How should 3,5-Dimethylbenzenesulfonyl chloride be handled safely?
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This compound is classified as Dangerous (GHS05, Signal Word: Danger) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., full-face particle respirator type N100 or P3 filter), is essential. Handle in a well-ventilated area and follow stringent safety protocols to avoid contact and inhalation.
How is 3,5-Dimethylbenzenesulfonyl chloride packed and exported?
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3,5-Dimethylbenzenesulfonyl chloride is packed according to international shipping regulations for hazardous materials. It is shipped under UN 3261, Hazard Class 8, Packing Group II. TSS is a global supplier and exporter experienced in handling and dispatching such chemicals worldwide.
How can I request a sample or quote for 3,5-Dimethylbenzenesulfonyl chloride?
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To request a sample or a quote for 3,5-Dimethylbenzenesulfonyl chloride, please contact our sales team via the website or email, providing your specific requirements and shipping details.
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