Methyl 2,2-dichloro-2-methoxyacetate
Methyl 2,2-dichloro-2-methoxyacetate (CAS 17640-25-4) is a chemical compound with the molecular formula Cl2C(OCH3)CO2CH3 and a molar mass of 172.99 g/mol. This ester is primarily utilized as a valuable building block in organic synthesis. Its specific reactivity makes it useful for introducing specific functionalities in the preparation of more complex molecules, particularly in the field of chemical research and development.
- Synonyms
- Cl2C(OCH3)CO2CH3

Organic Synthesis Intermediate
Methyl 2,2-dichloro-2-methoxyacetate serves as a key intermediate in various organic synthesis pathways. Its structure allows for controlled chemical transformations.
Preparation of Specialty Chemicals
It has been employed in the synthesis of methyl (Z)-α-methoxyacrylates through stereospecific two-carbon homologation of aldehydes. This highlights its utility in constructing specific molecular architectures.
Research and Development
As a functionalized building block, this compound is valuable in research laboratories for exploring novel synthetic routes and developing new chemical entities.
| Molecular weight | 172.99 |
|---|---|
| Linear formula | Cl2C(OCH3)CO2CH3 |
| Assay | 97% |
| Boiling point | 179-181 °C(lit.) |
| Density | 1.36 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.45(lit.) |
| Application | Methyl 2,2-dichloro-2-methoxyacetate was used in the preparation of methyl (Z)-α-methoxyacrylates via stereospecific two-carbon homologation of aldehydes under Barbier conditions1. |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2,2-dichloro-2-methoxyacetate used for?
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Methyl 2,2-dichloro-2-methoxyacetate is used as a building block in organic synthesis, including the preparation of methyl (Z)-α-methoxyacrylates.
What are the CAS number and formula for Methyl 2,2-dichloro-2-methoxyacetate?
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The CAS number is 17640-25-4 and the linear formula is Cl2C(OCH3)CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 2,2-dichloro-2-methoxyacetate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Methyl 2,2-dichloro-2-methoxyacetate be handled safely?
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Methyl 2,2-dichloro-2-methoxyacetate is classified as Danger, causing severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment including a full-face respirator, gloves, and goggles, in a well-ventilated area.
Is Methyl 2,2-dichloro-2-methoxyacetate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methyl 2,2-dichloro-2-methoxyacetate.
How can I request a quote or sample?
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Please contact our sales team via the website or by telephone to request a quote or sample of Methyl 2,2-dichloro-2-methoxyacetate.
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