N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide
N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide (CAS 1142192-06-0; molecular formula C13H19ClN2O3; molar mass 286.75 g/mol) is a substituted pyridine building block used in chemical synthesis. The molecule combines a chloropyridine core with a pivalamide group and a dimethyl acetal (a protected aldehyde), making it a versatile, multifunctional intermediate for medicinal chemistry and discovery research. Tech Serve Solutions supplies it as a research-grade halogenated heterocyclic building block to laboratories and manufacturers worldwide.
- Synonyms
- N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamideN-[2-chloro-6-(dimethoxymethyl)pyridin-3-yl]-2,2-dimethylpropanamide2,2-dimethyl-N-[2-chloro-6-(dimethoxymethyl)pyridin-3-yl]propanamideCAS 1142192-06-0

Heterocyclic building block
Serves as a functionalised pyridine scaffold in multi-step organic synthesis. The chloro substituent provides a handle for cross-coupling and nucleophilic substitution to elaborate the ring.
Pharmaceutical and discovery intermediate
Used as an intermediate in the preparation of more complex molecules during medicinal chemistry and drug-discovery programmes. It is offered for research and manufacturing use, not as a finished active ingredient.
Protected aldehyde equivalent
The dimethoxymethyl group is a dimethyl acetal that masks an aldehyde. It can be carried through synthetic sequences and unveiled to the corresponding pyridine carbaldehyde under controlled acidic conditions.
Amine-protected synthon
The pivalamide installs a sterically hindered, robust protecting group on the ring amine, allowing selective transformations elsewhere on the molecule before the amide is cleaved.
Cross-coupling substrate
The activated chloropyridine can participate in transition-metal-catalysed carbon-carbon and carbon-heteroatom bond formation, supporting library synthesis and structure-activity studies.
| Molecular weight | 286.75 |
|---|---|
| Empirical formula | C13H19ClN2O3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide used for?
+
It is used primarily as a building block and intermediate in chemical synthesis. The compound brings together a reactive chloropyridine, a protected aldehyde (dimethyl acetal) and a pivalamide-protected amine, which makes it useful for multi-step routes in medicinal chemistry and discovery research.
What is the CAS number and molecular formula of N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide?
+
The CAS number is 1142192-06-0. The molecular formula is C13H19ClN2O3, with a molecular weight of 286.75 g/mol.
What grade and purity does Tech Serve Solutions supply?
+
We supply this compound as a research- and synthesis-grade halogenated heterocyclic building block. We do not represent it as USP, BP or EP pharmacopoeia grade. A current specification and certificate of analysis are provided with each batch, and assay details can be confirmed on request before dispatch.
How should N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide be handled and stored?
+
Handle it as a laboratory research chemical using good chemical hygiene: wear suitable gloves, eye protection and a lab coat, and work in a well-ventilated area or fume hood. Store in a tightly closed container in a cool, dry place away from incompatible materials. Formal GHS hazard classification is not included in this listing, so please consult the Safety Data Sheet we provide before use.
How is N-(2-Chloro-6-(dimethoxymethyl)pyridin-3-yl)pivalamide packed, shipped and exported?
+
It is packed in appropriately sealed and labelled containers sized to the requested quantity, from gram research amounts to larger orders. Tech Serve Solutions exports worldwide with full documentation, including a certificate of analysis and Safety Data Sheet, and arranges compliant transport to suit the destination.
How do I request a sample or a quote?
+
Contact Tech Serve Solutions with the product name or CAS number 1142192-06-0 and your required quantity. We will confirm availability, current specification, lead time and packaging, and arrange a sample or formal quotation for your order.
▶ Related products

4-Amino-2-chloropyridine
C5H5ClN2
Heterocyclic Building Blocks
4-Ethynyl-1-methyl-1H-pyrazole
C6H6N2
Heterocyclic Building Blocks
4-Hydroxyquinoline-3-carboxylic acid ethyl ester
C12H11NO3
Heterocyclic Building Blocks
4-isocyanatopyridine
C6H4N2O
Heterocyclic Building Blocks
5-Chloro-2,8-dimethylquinoline
Heterocyclic Building Blocks

5-Chloro-2-methylene-1,3,3-trimethylindoline
Heterocyclic Building Blocks

5-Chloro-2-thiophenecarbonitrile
Heterocyclic Building Blocks

5-ethynyl-1H-pyrazole
C5H4N2
Heterocyclic Building Blocks▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis