N-(2-Chloro-6-formylpyridin-3-yl)pivalamide
N-(2-Chloro-6-formylpyridin-3-yl)pivalamide (CAS 1142191-76-1, C11H13ClN2O2, molar mass 240.69 g/mol) is a halogenated pyridine building block used in pharmaceutical and fine-chemical synthesis. The structure combines a reactive aldehyde, a displaceable 2-chloro substituent and a 3-amino group protected as a pivalamide, giving three orthogonal handles for cross-coupling, condensation and deprotection. Tech Serve Solutions supplies it as a research-grade intermediate for laboratory and process development.
- Synonyms
- N-(2-Chloro-6-formylpyridin-3-yl)pivalamideN-(2-Chloro-6-formyl-3-pyridinyl)-2,2-dimethylpropanamideN-(2-chloro-6-formylpyridin-3-yl)-2,2-dimethylpropanamide2,2-dimethyl-N-(2-chloro-6-formylpyridin-3-yl)propanamideCAS 1142191-76-1
Pharmaceutical intermediate
Serves as a multifunctional pyridine scaffold in the synthesis of drug candidates and active pharmaceutical ingredients. Its three reactive sites allow concise, convergent routes to more complex heterocyclic targets.
Cross-coupling substrate
The 2-chloro group on the electron-poor pyridine ring participates in palladium-catalysed cross-coupling reactions such as Suzuki, Buchwald-Hartwig and related transformations, enabling carbon-carbon and carbon-nitrogen bond formation.
Aldehyde-directed functionalisation
The 6-formyl group is a versatile handle for reductive amination, condensation, olefination and reduction, providing access to imines, amines, alcohols and extended frameworks from a single intermediate.
Protected aminopyridine handle
The 3-amino function is masked as a pivalamide, a robust protecting group that survives many reaction conditions and can be removed to reveal the free amine for further elaboration.
Research and discovery chemistry
Used in medicinal-chemistry and library synthesis where a halogenated, polysubstituted pyridine core is required. Suited to laboratory-scale exploration and process-development work.
| Molecular weight | 240.69 |
|---|---|
| Empirical formula | C11H13ClN2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Chloro-6-formylpyridin-3-yl)pivalamide used for?
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It is used as a building block and intermediate in pharmaceutical and fine-chemical synthesis. The molecule offers an aldehyde, a 2-chloro leaving group and a protected amino group, making it useful for cross-coupling, reductive amination, condensation and the construction of substituted pyridine scaffolds.
What is the CAS number and molecular formula of N-(2-Chloro-6-formylpyridin-3-yl)pivalamide?
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The CAS number is 1142191-76-1 and the molecular formula is C11H13ClN2O2, with a molecular weight of 240.69 g/mol. It belongs to the halogenated heterocyclic building blocks and pyridine classes.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research-grade synthetic intermediate suitable for laboratory and process-development use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis with the actual assay for each lot is provided on request.
How should N-(2-Chloro-6-formylpyridin-3-yl)pivalamide be handled and stored?
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Handle as a research chemical using good laboratory practice: wear suitable gloves, eye protection and a lab coat, avoid dust formation, and work with adequate ventilation. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. Always consult the Safety Data Sheet, which carries the full classification, before use; an SDS is supplied with every order.
How is N-(2-Chloro-6-formylpyridin-3-yl)pivalamide packed, shipped and exported?
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The material is packed in appropriately sealed, labelled containers sized to the requested quantity, from gram to bulk scale. As an established exporter, Tech Serve Solutions arranges compliant international shipping with full documentation, including the Certificate of Analysis and Safety Data Sheet, to meet destination-country import requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 1142191-76-1, the quantity required and your delivery destination. We will confirm availability, lead time and documentation and respond with a quotation for your enquiry.
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