O-tert-Butyl-L-serine methyl ester hydrochloride
O-tert-Butyl-L-serine methyl ester hydrochloride (CAS 17114-97-5) is a protected amino acid derivative with a molecular weight of 211.69 g/mol. It is a valuable building block in organic synthesis, particularly within peptide chemistry and the development of complex molecules. Its structure incorporates a tert-butyl ester and a methyl ester, offering distinct protecting group strategies for synthetic routes. This compound finds utility in chemical biology and general chemical synthesis.

Peptide Synthesis
Serves as a protected serine residue for incorporation into peptide chains. The tert-butyl ester protects the carboxylic acid, while the amine is protected by the hydrochloride salt, allowing for controlled coupling reactions.
Organic Synthesis
A versatile intermediate for the construction of more complex organic molecules. It can be employed in various synthetic strategies where a functionalised serine moiety is required.
Chemical Biology Research
Used in the synthesis of modified amino acids and peptides for biochemical studies, enabling investigations into protein function and interactions.
| Molecular weight | 211.69 |
|---|---|
| Linear formula | (CH3)3COCH2CH(NH2)COOCH3 · HCl |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-tert-Butyl-L-serine methyl ester hydrochloride used for?
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This compound is primarily used as a building block in organic synthesis, particularly in peptide chemistry and chemical biology research for the construction of complex organic molecules and modified peptides.
What is the CAS number and molecular formula for O-tert-Butyl-L-serine methyl ester hydrochloride?
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The CAS number is 17114-97-5. The linear formula is (CH3)3COCH2CH(NH2)COOCH3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-tert-Butyl-L-serine methyl ester hydrochloride with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should O-tert-Butyl-L-serine methyl ester hydrochloride be handled?
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When handling, wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
Is O-tert-Butyl-L-serine methyl ester hydrochloride a controlled substance?
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The provided data does not indicate that O-tert-Butyl-L-serine methyl ester hydrochloride is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the compliant packing, shipping, and export of O-tert-Butyl-L-serine methyl ester hydrochloride worldwide.
How can I request a sample or quote for this product?
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Please contact our sales team directly through our website or by phone to request a sample or a formal quotation for O-tert-Butyl-L-serine methyl ester hydrochloride.
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