O-tert-Butyl-L-threonine tert-butyl ester acetate salt
O-tert-Butyl-L-threonine tert-butyl ester acetate salt (CAS 5854-77-3) is a derivative of the essential amino acid threonine. With a molecular formula of C12H25NO3 · C2H4O2 and a molecular weight of 291.38, this compound is valuable in chemical synthesis and peptide chemistry. It serves as a protected building block for constructing complex peptides and other organic molecules, particularly where the threonine side chain requires specific protection strategies.
Peptide Synthesis
Utilised as a protected amino acid derivative in solid-phase or solution-phase peptide synthesis. Its tert-butyl ester protection allows for selective deprotection strategies during the assembly of peptide chains.
Organic Synthesis
Serves as a chiral building block in the synthesis of complex organic molecules and pharmaceuticals. The threonine backbone offers a stereochemically defined scaffold for further chemical modification.
Chemical Biology Research
Employed in research settings to introduce modified amino acid residues into peptides or proteins for studying biological function or developing novel bioconjugates.
| Molecular weight | 291.38 |
|---|---|
| Empirical formula | C12H25NO3 · C2H4O2 |
| Assay | ≥95.0% (T) |
| Optical activity | [α]20/D −10±1°, c = 1% in methanol |
| Melting point | 59-61 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-tert-Butyl-L-threonine tert-butyl ester acetate salt used for?
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This compound is primarily used as a protected amino acid derivative in peptide synthesis and as a chiral building block in organic synthesis and chemical biology research.
What is the CAS number and chemical formula?
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The CAS number is 5854-77-3, and the chemical formula is C12H25NO3 · C2H4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥95.0% (T). This is a technical/research grade material and is not represented as USP/BP/EP.
How should O-tert-Butyl-L-threonine tert-butyl ester acetate salt be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Ensure adequate ventilation. It carries a WGK Germany rating of 3.
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport according to international regulations.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone. We will be happy to assist you with your specific requirements.
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