3-Fluoro-4-methylbenzenesulfonyl chloride
3-Fluoro-4-methylbenzenesulfonyl chloride (CAS: 90260-13-2; Formula: FC6H3(CH3)SO2Cl; MW: 208.64) is a key aryl fluorinated building block. This sulfonyl chloride derivative serves as a versatile intermediate in organic synthesis, particularly for introducing the 3-fluoro-4-methylbenzenesulfonyl moiety into various molecular structures. Its reactivity makes it valuable in the development of novel compounds across chemical research and industrial applications, including pharmaceuticals and agrochemicals.

Organic Synthesis Intermediate
Utilised as a reactive intermediate in the construction of complex organic molecules. The compound facilitates the introduction of a fluorinated arylsulfonyl group, which is significant in medicinal chemistry and material science.
Pharmaceutical Research
Serves as a building block in the synthesis of potential pharmaceutical agents. Its fluorinated structure can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
Applied in the research and development of new agrochemical compounds. Fluorinated substituents can enhance the efficacy and stability of pesticides and herbicides.
Material Science
Incorporated into the synthesis of specialized polymers and materials where fluorination confers desirable properties such as thermal stability and chemical resistance.
| Molecular weight | 208.64 |
|---|---|
| Linear formula | FC6H3(CH3)SO2Cl |
| Assay | 97% |
| Melting point | 46-50 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-methylbenzenesulfonyl chloride used for?
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3-Fluoro-4-methylbenzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and novel materials.
What is the CAS number and chemical formula for 3-Fluoro-4-methylbenzenesulfonyl chloride?
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The CAS number is 90260-13-2, and the chemical formula is FC6H3(CH3)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-methylbenzenesulfonyl chloride with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary hazards associated with 3-Fluoro-4-methylbenzenesulfonyl chloride?
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This compound is classified with the GHS symbol GHS05 and signal word Danger. It causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, faceshields, and chemical-resistant gloves, must be worn.
Is 3-Fluoro-4-methylbenzenesulfonyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Fluoro-4-methylbenzenesulfonyl chloride, and can fulfil international orders.
How can I request a quote or sample for 3-Fluoro-4-methylbenzenesulfonyl chloride?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (90260-13-2).
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