3-Fluoro-4-methylphenylboronic acid

CAS 168267-99-0FC6H3(CH3)B(OH)2Chemical Synthesis

3-Fluoro-4-methylphenylboronic acid (CAS: 168267-99-0), with the molecular formula C7H8BO2F and a molecular weight of 153.95 g/mol, is a vital organoboron compound. It serves as a key reactant in regioselective Suzuki coupling reactions, contributing to the synthesis of complex organic molecules. Tech Serve Solutions supplies this high-quality intermediate for research and development applications in organic synthesis and medicinal chemistry.

IUPAC: 3-Fluoro-4-methylbenzeneboronic acid
Synonyms: 3-Fluoro-4-methylbenzeneboronic acid

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3-Fluoro-4-methylphenylboronic acid (FC6H3(CH3)B(OH)2) — chemical structure, CAS 168267-99-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical Synthesis

01 /Applications

Suzuki Coupling Reagent

3-Fluoro-4-methylphenylboronic acid is utilised as a coupling partner in regioselective Suzuki-Miyaura cross-coupling reactions. This enables the formation of carbon-carbon bonds, crucial for constructing elaborate molecular architectures.

Organic Synthesis Intermediate

This boronic acid is a valuable building block in synthetic organic chemistry. Its specific substitution pattern allows for targeted functionalisation in the development of novel compounds.

Medicinal Chemistry Research

It finds application in the synthesis of potential drug candidates and biologically active molecules, where the fluorinated methylphenyl moiety is incorporated into target structures.

02 /Properties

Molecular weight	153.95
Linear formula	FC6H3(CH3)B(OH)2
Application	Reactant for:• Regioselective Suzuki coupling1,2
Melting point	232-237 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

168267-99-0

MDL number

MFCD02683115

PubChem substance

24880364

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Fluoro-4-methylphenylboronic acid used for?

3-Fluoro-4-methylphenylboronic acid is primarily used as a reactant for regioselective Suzuki coupling reactions in organic synthesis and medicinal chemistry research.

What are the CAS number and chemical formula for 3-Fluoro-4-methylphenylboronic acid?

The CAS number is 168267-99-0 and the chemical formula is FC6H3(CH3)B(OH)2, with a molecular weight of 153.95 g/mol.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound for research purposes. Purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or for food/nutraceutical use.

What are the safety and handling recommendations for this chemical?

This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling information.

How is 3-Fluoro-4-methylphenylboronic acid shipped and exported?

Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals and laboratory reagents, adhering to all relevant shipping and export regulations.