3-Fluoro-4-nitrophenol
3-Fluoro-4-nitrophenol (CAS: 394-41-2, Formula: FC6H3(NO2)OH) is a fluorinated organic building block with a molecular weight of 157.10 g/mol. This compound serves as a valuable intermediate in chemical synthesis, particularly for the creation of complex organic molecules. Its applications include the preparation of heterocyclic compounds like benzimidazoles and quinoxalin-2-ones, as well as the synthesis of other functionalized aromatic compounds used in research and development.
Synthesis of Benzimidazoles and Quinoxalin-2-ones
3-Fluoro-4-nitrophenol is utilized in solid-phase synthesis methodologies to construct benzimidazole and quinoxalin-2-one derivatives. These heterocyclic compounds are often explored for their potential pharmaceutical properties.
Preparation of Substituted Aromatic Ethers
The compound can be employed in the synthesis of functionalized aromatic ethers, such as 2-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene. This demonstrates its utility in creating complex molecules with ether linkages.
Fluorinated Building Block in Organic Synthesis
As a key fluorinated aryl building block, 3-Fluoro-4-nitrophenol offers a reactive site for incorporating fluorine and a nitro group into target molecules. This is valuable in medicinal chemistry and materials science research.
| Molecular weight | 157.10 |
|---|---|
| Linear formula | FC6H3(NO2)OH |
| Assay | 99% |
| Application | 3-Fluoro-4-nitrophenol was used in solid phase synthesis of benzimidazoles and quinoxalin-2-ones1. It was also used in the synthesis of 2-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene2. |
| Melting point | 93-95 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-nitrophenol used for?
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3-Fluoro-4-nitrophenol is used as a building block in chemical synthesis, particularly for the preparation of benzimidazoles, quinoxalin-2-ones, and other functionalized aromatic compounds.
What is the CAS number and chemical formula for 3-Fluoro-4-nitrophenol?
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The CAS number is 394-41-2, and the chemical formula is FC6H3(NO2)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-nitrophenol with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any pharmacopoeia grade.
How should 3-Fluoro-4-nitrophenol be handled safely?
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3-Fluoro-4-nitrophenol is classified as Dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
Does Tech Serve Solutions export 3-Fluoro-4-nitrophenol?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Fluoro-4-nitrophenol.
How can I request a sample or quote for 3-Fluoro-4-nitrophenol?
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To request a sample or a quotation for 3-Fluoro-4-nitrophenol, please contact our sales department through the website or by phone.
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