3-Fluoro-4-pyridinecarbaldehyde
3-Fluoro-4-pyridinecarbaldehyde (CAS: 40273-47-0), a fluorinated pyridine derivative with the molecular formula C6H4FNO and a molecular weight of 125.10 g/mol. This aldehyde serves as a versatile building block in organic synthesis. Its primary applications are in the research and development of novel pharmaceutical agents and advanced materials, leveraging the unique properties imparted by the fluorine atom and the pyridine ring. It is ideal for introducing fluoropyridyl moieties into target molecules.
- IUPAC
- 3-Fluoroisonicotinaldehyde
- Synonyms
- 3-Fluoroisonicotinaldehyde

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), particularly where a fluoropyridine scaffold is desired. It is a key component in developing new drug candidates for various therapeutic areas.
Organic Synthesis Building Block
Serves as a valuable reagent in complex organic synthesis, enabling the construction of intricate molecular architectures. The aldehyde functionality allows for a range of derivatisation reactions.
Materials Science
Can be employed in the development of advanced materials, such as functional polymers or organic electronics, where specific electronic or structural properties are required.
| Molecular weight | 125.10 |
|---|---|
| Empirical formula | C6H4FNO |
| Assay | 97% |
| Boiling point | 70 °C/25 mmHg(lit.) |
| Density | 1.2550 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5170(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 67 °C / 152.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-pyridinecarbaldehyde used for?
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3-Fluoro-4-pyridinecarbaldehyde is primarily used as a building block in organic synthesis, especially in the development of pharmaceuticals and advanced materials. It is employed to introduce the 3-fluoro-4-pyridyl group into target molecules.
What is the CAS number and formula for 3-Fluoro-4-pyridinecarbaldehyde?
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The CAS number is 40273-47-0 and the empirical formula is C6H4FNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-pyridinecarbaldehyde with a minimum assay of 97%. This product is not graded as USP, BP, or EP unless explicitly stated.
How should 3-Fluoro-4-pyridinecarbaldehyde be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type ABEK respirator filter recommended). It is classified as harmful if swallowed, causes skin irritation, allergic skin reaction, causes serious eye irritation, and may cause respiratory irritation (H302, H315, H317, H319, H335).
How is 3-Fluoro-4-pyridinecarbaldehyde shipped and exported?
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3-Fluoro-4-pyridinecarbaldehyde is shipped and exported according to relevant transport regulations, with packaging suitable for hazardous materials (NA 1993 / PGIII).
How can I request a quote or sample?
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To request a quote or sample of 3-Fluoro-4-pyridinecarbaldehyde, please contact our sales team via the website or by phone.
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