3-Fluoro-4-pyridineboronic acid pinacol ester
3-Fluoro-4-pyridineboronic acid pinacol ester (CAS: 458532-88-2) is a valuable organoboron compound with the empirical formula C11H15BFNO2 and a molecular weight of 223.05 g/mol. It functions as a key building block in organic synthesis, particularly in cross-coupling reactions. This heteroaryl boronate ester is widely utilised in the development of novel pharmaceutical intermediates and complex organic molecules, offering a reliable route to introduce fluoropyridine moieties.
- IUPAC
- 3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)pyridine
- Synonyms
- 3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)pyridine
Organic Synthesis Intermediate
This pinacol ester serves as a crucial intermediate in Suzuki-Miyaura cross-coupling reactions. It enables the efficient formation of carbon-carbon bonds, facilitating the synthesis of complex fluoropyridine-containing molecules.
Pharmaceutical Research
It is employed in the research and development of new pharmaceutical agents. The fluoropyridine motif is present in various biologically active compounds, making this reagent valuable for drug discovery efforts.
Material Science
This compound can be utilised in the synthesis of advanced materials where the unique electronic and structural properties of fluoropyridine units are desired.
| Molecular weight | 223.05 |
|---|---|
| Empirical formula | C11H15BFNO2 |
| Assay | 95% |
| Melting point | 124-128 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-pyridineboronic acid pinacol ester used for?
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3-Fluoro-4-pyridineboronic acid pinacol ester is primarily used as an intermediate in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research for the development of novel drug candidates.
What is the CAS number and empirical formula for this compound?
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The CAS number is 458532-88-2 and the empirical formula is C11H15BFNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 3-Fluoro-4-pyridineboronic acid pinacol ester be handled safely?
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This compound is a Warning irritant. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure good ventilation. Refer to the safety data sheet for comprehensive handling instructions.
Is this chemical a controlled substance?
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Based on the provided data, this chemical is not indicated as a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, can arrange for suitable packing and export documentation for 3-Fluoro-4-pyridineboronic acid pinacol ester according to international regulations.
How can I request a quote or sample?
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To request a quote or sample of 3-Fluoro-4-pyridineboronic acid pinacol ester, please contact the Tech Serve Solutions sales department via our website or direct inquiry channels.
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