AMN082
AMN082 (CAS: 97075-46-2), with the molecular formula C28H28N2 · 2HCl and a molecular weight of 465.46 g/mol, is a selective allosteric mGluR 7 receptor agonist. Supplied as a white to off-white solid, this compound is primarily used in research settings to investigate the role of metabotropic glutamate receptor 7 in cellular processes. Its applications include studying its effects on cAMP accumulation and stress hormone release.
- IUPAC
- N,N′-Dibenzhydrylethane-1,2-diamine dihydrochloride
- Synonyms
- N,N′-Dibenzhydrylethane-1,2-diamine dihydrochloride
Neuroscience Research
AMN082 is utilized as a tool compound to explore the function of mGluR 7 receptors in the central nervous system, particularly within the medial prefrontal cortex. Its agonistic activity allows researchers to probe receptor-mediated signaling pathways.
Cell Signaling Studies
This compound serves to investigate the downstream effects of mGluR 7 activation, such as its impact on forskolin-stimulated cAMP accumulation. It aids in understanding complex cellular signaling cascades.
Stress Hormone Research
AMN082 has been employed in studies examining the relationship between mGluR 7 receptor activity and the release of stress hormones, contributing to a deeper understanding of neuroendocrine regulation.
| Molecular weight | 465.46 |
|---|---|
| Empirical formula | C28H28N2 · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: ≥5 mg/mL |
| Storage temperature | −20°C |
| Application | AMN082 is a selective allosteric mGluR 7 receptor agonist and has been used to study the role of this glutamate receptor type in the medial prefrontal cortex in mice. AMN082 inhibits forskolin-stimulated cAMP accumulation, and stimulates not only GTPγS binding but also the release of stress hormones. |
Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is AMN082 used for?
+
AMN082 is used in scientific research, primarily as a selective allosteric agonist for the mGluR 7 receptor, to study its role in the medial prefrontal cortex, its effects on cAMP accumulation, and the release of stress hormones.
What are the CAS number and formula for AMN082?
+
The CAS number for AMN082 is 97075-46-2, and its empirical formula is C28H28N2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies AMN082 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should AMN082 be handled safely?
+
AMN082 is classified as harmful if swallowed and very toxic to aquatic life. When handling, use a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid release into the environment.
How is AMN082 packed and shipped?
+
AMN082 is typically supplied as a solid and is stored desiccated at -20°C. For export, it is packaged according to international shipping regulations for hazardous materials (UN 3077).
How can I request a sample or quote for AMN082?
+
Please contact our sales team through the website or by phone to request a sample or obtain a quotation for AMN082.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis