AMPSO
AMPSO (CAS: 68399-79-1, C7H17NO5S) is a high-purity biological buffer with a molecular weight of 227.28 g/mol. Characterised by its pKa of 9.0 at 25°C, AMPSO offers excellent buffering capacity within a pH range of 8.3 to 9.7. Its high solubility in water and low UV absorption make it suitable for various biochemical and biological research applications, particularly where stable pH control is critical.
- IUPAC
- N-(1,1-Dimethyl-2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid

Biological Buffering Agent
AMPSO is utilised in biological and biochemical research to maintain stable pH conditions. Its pKa value makes it particularly effective for applications requiring a buffered environment between pH 8.3 and 9.7, supporting enzymatic assays and cell culture media.
Biochemical Research
This compound serves as a reagent in various biochemical investigations. Its low absorption at 260 nm and 280 nm, combined with its buffering capabilities, are advantageous in spectroscopic studies and protein purification processes.
Electrophoresis and Chromatography
AMPSO can be incorporated into buffer systems for electrophoresis and chromatography. Its ionic properties and buffering capacity contribute to stable running conditions and reproducible results in these separation techniques.
| Molecular weight | 227.28 |
|---|---|
| Empirical formula | C7H17NO5S |
| Assay | ≥99% (titration) |
| Solubility | H2O: soluble1 M at 20 °C, clear, colorless |
| Impurities tested | ≤0.0005% Phosphorus (P)≤0.1% Insoluble matter |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Al: ≤0.0005%Ca: ≤0.0005%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.005%Mg: ≤0.0005%NH4+: ≤0.05%Na: ≤0.01%Pb: ≤0.001%Zn: ≤0.0005% |
| Anion traces | chloride (Cl-): ≤0.1%sulfate (SO42-): ≤0.05% |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioXtra |
|---|---|
| Pka 25 °C | 9.0 |
| Absorption | A1M/260, H2O ≤0.1A1M/280, H2O ≤0.05 |
| Useful Ph Range | 8.3 - 9.7 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is AMPSO used for?
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AMPSO is primarily used as a biological buffer in biochemical and biological research, particularly effective in maintaining stable pH between 8.3 and 9.7 for enzymatic assays, cell culture, and separation techniques.
What is the CAS number and chemical formula for AMPSO?
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The CAS number for AMPSO is 68399-79-1, and its chemical formula is C7H17NO5S.
What grade and purity does Tech Serve Solutions supply for AMPSO?
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Tech Serve Solutions supplies AMPSO with an assay of ≥99% by titration. This product is designated as BioXtra, suitable for research purposes. It is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the main safety considerations when handling AMPSO?
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When handling AMPSO, it is essential to wear safety goggles and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if dust is generated. The compound is classified with WGK Germany 3, indicating it is hazardous to water.
How is AMPSO packed and shipped?
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AMPSO is packed according to industry best practices for fine chemicals to ensure stability during transit. Tech Serve Solutions is a global supplier and exporter, capable of handling international shipments in compliance with shipping regulations.
How can I request a sample or quote for AMPSO?
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To request a sample or a quote for AMPSO, please contact the Tech Serve Solutions sales team through the website or by phone, providing your specific requirements and shipping details.
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