3-Fluoro-4-methylphenylmagnesium bromide solution
3-Fluoro-4-methylphenylmagnesium bromide solution (CAS 185077-02-5), with a molecular weight of 213.33 g/mol, is a valuable Grignard reagent. It is supplied as a 0.5 M solution in Tetrahydrofuran (THF). This organometallic compound serves as a key building block in organic synthesis, facilitating the formation of carbon-carbon bonds and enabling the construction of complex molecular architectures for various research and development purposes.
Organic Synthesis Intermediate
Utilised as a nucleophilic reagent in the synthesis of complex organic molecules. It is particularly useful for introducing the 3-fluoro-4-methylphenyl moiety into target structures.
Pharmaceutical Research
Serves as a versatile precursor in the development of novel pharmaceutical compounds. Its specific substitution pattern can be crucial for modulating the biological activity of drug candidates.
Agrochemical Development
Employed in the synthesis of new agrochemical agents, where the fluorinated aromatic ring can impart desirable properties such as enhanced efficacy or stability.
Materials Science
Can be incorporated into the synthesis of advanced materials and polymers, where its unique electronic and structural characteristics may lead to novel material properties.
| Molecular weight | 213.33 |
|---|---|
| Linear formula | FC6H3(CH3)MgBr |
| Boiling point | 65 °C |
| Density | 0.953 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-methylphenylmagnesium bromide solution used for?
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3-Fluoro-4-methylphenylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis for introducing the 3-fluoro-4-methylphenyl group into various organic molecules, particularly in pharmaceutical and agrochemical research.
What is the CAS number and formula for 3-Fluoro-4-methylphenylmagnesium bromide solution?
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The CAS number is 185077-02-5, and the linear formula is FC6H3(CH3)MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-methylphenylmagnesium bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with this product?
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This product is a Danger signal word chemical, flammable (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides and requires careful handling and storage, away from heat and ignition sources, with appropriate personal protective equipment.
How is 3-Fluoro-4-methylphenylmagnesium bromide solution packed, shipped, and exported?
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This solution is typically packed in specialised containers suitable for reactive organometallic reagents and flammable liquids. Shipping and export are conducted in compliance with all relevant international regulations for hazardous materials.
How can I request a sample or quote for 3-Fluoro-4-methylphenylmagnesium bromide solution?
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To request a sample or a quote, please visit the Tech Serve Solutions website or contact our sales department directly, providing the product name and CAS number.
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