O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000
O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000 (CAS: 159156-95-3) is a protected polyethylene glycol derivative with a molecular weight of approximately 5,000 Da. It features a Boc-protected amine group at one end of the PEG chain and a hydroxyl group at the other. This functionalisation makes it a versatile building block in chemical synthesis, particularly for PEGylation applications.
- IUPAC
- HO-PEG-NH-BOC 5,000
- Synonyms
- HO-PEG-NH-BOC 5,000O-(2-(tert-butoxycarbonylamino)ethyl)-omega-methoxy-poly(oxy-1,2-ethanediyl)tert-butyl (2-(2-(2-((poly(oxy-1,2-ethanediyl))oxy)ethoxy)ethyl)carbamate
![O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000 (C29H59NO14) — chemical structure, CAS 159156-95-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F159156-95-3.png&w=3840&q=75)
PEGylation Reagent
This compound serves as a key reagent for PEGylation, enabling the attachment of polyethylene glycol chains to other molecules. This process can improve drug solubility, stability, and pharmacokinetic profiles.
Bioconjugation
Its bifunctional nature allows for facile conjugation to biomolecules such as proteins, peptides, and antibodies. The Boc-protected amine can be deprotected and subsequently reacted with activated molecules.
Drug Delivery Systems
Used in the development of advanced drug delivery systems, it can be incorporated into nanoparticles, liposomes, or micelles to enhance drug targeting and controlled release.
Surface Modification
Applied to modify the surfaces of materials and nanoparticles, imparting hydrophilic properties and reducing non-specific binding, which is crucial for biomedical devices and diagnostics.
| Linear formula | HO(CH2CH2O)nCH2CH2NHCOOC(CH3)3 |
|---|
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000 used for?
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O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000 is primarily used as a PEGylation reagent for attaching polyethylene glycol chains to molecules, in bioconjugation, drug delivery systems, and surface modification.
What is the CAS number and formula for O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000?
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The CAS number is 159156-95-3. The linear formula is HO(CH2CH2O)nCH2CH2NHCOOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. It is not supplied as USP, BP, or EP grade.
What safety precautions should be taken when handling this chemical?
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When handling, wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is this chemical hazardous?
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This chemical is classified under WGK 2 in Germany, indicating it is hazardous to water. Please consult the SDS for full hazard details and safe handling procedures.
How is O-[2-(Boc-amino)ethyl]polyethylene glycol 5,000 packed, shipped, and exported?
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We ensure secure and compliant packaging for domestic and international shipments. As an experienced global exporter, we adhere to all relevant regulations for shipping chemical products.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please use the contact form on our website or reach out to our sales team directly. Please reference the product name and CAS number.
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