Methyl α-bromoacrylate
Methyl α-bromoacrylate (CAS: 4519-46-4, Formula: C4H5BrO2) is a functionalised acrylate ester with a molecular weight of 164.99 g/mol. This compound serves as a versatile building block in organic synthesis, particularly for introducing acrylate moieties into complex molecules. Its reactivity makes it valuable in the development of novel materials and pharmaceutical intermediates, offering precise control in polymerisation and functional group transformations.

Organic Synthesis Intermediate
Methyl α-bromoacrylate is employed as a key intermediate in the synthesis of various organic compounds. It readily participates in nucleophilic substitution reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds, crucial for constructing complex molecular architectures.
Monomer for Polymerisation
As an acrylate monomer, it can be polymerised to create specialised polymers. The presence of the bromine atom allows for further functionalisation of the resulting polymer chains, leading to materials with tailored properties for advanced applications.
Pharmaceutical and Agrochemical Research
This compound is utilised in the research and development of new pharmaceutical and agrochemical agents. Its structure is amenable to incorporation into bioactive molecules, contributing to the search for novel therapeutic or crop protection agents.
| Molecular weight | 164.99 |
|---|---|
| Empirical formula | C4H5BrO2 |
| Assay | 95% |
| Boiling point | 70-75 °C/48 mmHg(lit.) |
| Density | 1.556 g/mL at 25 °C(lit.) |
| Storage temperature | −20°C |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl α-bromoacrylate used for?
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Methyl α-bromoacrylate is primarily used as an intermediate in organic synthesis, a monomer for creating specialised polymers, and in research for pharmaceutical and agrochemical development.
What are the CAS number and formula for Methyl α-bromoacrylate?
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The CAS number is 4519-46-4 and the molecular formula is C4H5BrO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl α-bromoacrylate with an assay of 95%. TSS does not represent this product as USP, BP, or EP grade.
How should Methyl α-bromoacrylate be handled safely?
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Handle Methyl α-bromoacrylate with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator. It is a flammable liquid and irritant; refer to the safety data sheet for detailed handling procedures.
How is Methyl α-bromoacrylate packed and exported?
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Methyl α-bromoacrylate is packed and exported according to international regulations for hazardous materials, including UN 1993 classification.
How can I request a sample or quote for Methyl α-bromoacrylate?
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To request a sample or quote, please contact the TSS sales team through our website or by phone, providing your specific requirements.
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