2-(tert-Butyldimethylsilyloxy)naphthalene-6-boronic acid
2-(tert-Butyldimethylsilyloxy)naphthalene-6-boronic acid (CAS 179942-45-1, C16H23BO3Si) is a specialised organoboronic acid derivative. With a molecular weight of 302.25 g/mol, this compound functions as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure allows for diverse functionalisation, making it a key intermediate for the development of complex organic molecules in research and development settings.
- IUPAC
- tert-Butyl[[6-(dihydroxyboryl)-2-naphthyl]oxy]dimethylsilane,[6-[(tert-Butyldimethylsilyl)oxy]naphthalen-2-yl]boronic acid
- Synonyms
- tert-Butyl[[6-(dihydroxyboryl)-2-naphthyl]oxy]dimethylsilane[6-[(tert-Butyldimethylsilyl)oxy]naphthalen-2-yl]boronic acid

Organic Synthesis Intermediate
Utilised as a versatile building block in the synthesis of complex organic molecules. Its aryl boronic acid functionality is well-suited for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds.
Pharmaceutical Research
A key intermediate in the development of novel pharmaceutical compounds. Its naphthalene and boronic acid moieties can be incorporated into molecular scaffolds for drug discovery efforts.
Materials Science
Can be employed in the synthesis of advanced materials, such as organic semiconductors or specialised polymers, where specific electronic or optical properties are desired.
| Molecular weight | 302.25 |
|---|---|
| Empirical formula | C16H23BO3Si |
| Application | May contain varying amounts of anhydride |
| Melting point | 244-248 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(tert-Butyldimethylsilyloxy)naphthalene-6-boronic acid used for?
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This compound is primarily used as a building block and intermediate in organic synthesis, particularly for cross-coupling reactions and in the development of pharmaceuticals and advanced materials.
What are the CAS number and formula for this compound?
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The CAS number is 179942-45-1 and the empirical formula is C16H23BO3Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a technical or research grade. We do not represent it as USP, BP, or EP grade.
What are the main safety hazards associated with this chemical?
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This compound is classified with GHS07, carries a Warning signal word, and has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used.
How is this chemical typically packed and shipped?
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This chemical is packed and shipped according to international regulations for hazardous materials, suitable for export.
How can I request a sample or quote for 2-(tert-Butyldimethylsilyloxy)naphthalene-6-boronic acid?
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To request a sample or quote, please contact our sales department through the website or by email, providing your specific requirements.
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