2-(tert-Butyldimethylsilyloxy)cyclohexanone
2-(tert-Butyldimethylsilyloxy)cyclohexanone (CAS: 74173-08-3), with the molecular formula C12H24O2Si and a molecular weight of 228.40 g/mol, is a versatile organic building block. This silyloxy ketone is valuable in organic synthesis, serving as a protected form of 2-hydroxycyclohexanone. Its chemical structure facilitates controlled reactions in multi-step syntheses, making it a useful intermediate for creating more complex molecules in research and development.

Organic Synthesis Intermediate
This compound serves as a protected ketone in multi-step organic syntheses. The tert-butyldimethylsilyl (TBS) ether protects the hydroxyl group, allowing selective reactions at the carbonyl centre. This enables the construction of complex molecules where precise control over functional group reactivity is required.
Building Block for Pharmaceutical Research
As a functionalised cyclic ketone, it is employed as a key building block in the synthesis of novel pharmaceutical agents. Its structure can be incorporated into scaffolds targeting various biological pathways, aiding drug discovery efforts.
Reagent in Fine Chemical Manufacturing
Used in the production of fine chemicals, this silyloxy ketone allows for controlled chemical transformations. Its application supports the development of specialised materials and advanced intermediates for various industrial sectors.
| Molecular weight | 228.40 |
|---|---|
| Empirical formula | C12H24O2Si |
| Assay | 97% |
| Boiling point | 55-59 °C/0.05 mmHg(lit.) |
| Density | 1.969 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(tert-Butyldimethylsilyloxy)cyclohexanone used for?
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2-(tert-Butyldimethylsilyloxy)cyclohexanone (CAS: 74173-08-3) is primarily used as a building block and intermediate in organic synthesis, particularly in the preparation of complex molecules and pharmaceutical research.
What are the CAS number and molecular formula?
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The CAS number for 2-(tert-Butyldimethylsilyloxy)cyclohexanone is 74173-08-3, and its molecular formula is C12H24O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(tert-Butyldimethylsilyloxy)cyclohexanone with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling this chemical?
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This chemical requires the use of eyeshields and gloves for protection. It is a combustible liquid with a flash point of 93 °C (199.4 °F) and is classified under UN 1993, PGIII for transportation.
How is this product packed and shipped?
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This product is suitable for export and is typically shipped with appropriate safety documentation. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of 2-(tert-Butyldimethylsilyloxy)cyclohexanone, please contact our sales team through the website or by phone, providing your specific requirements.
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