2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole
2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole (CAS: 160425-48-9, Formula: C10H20N2Si) is a specialised organic compound with a molecular weight of 196.36 g/mol. This imidazole derivative serves as a versatile building block in organic synthesis. Its unique structure, featuring a silyl protecting group and a methylated imidazole ring, makes it valuable for introducing specific functionalities in complex molecule construction, particularly within pharmaceutical and fine chemical research.

Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis pathways. The tert-butyldimethylsilyl group acts as a robust protecting group for the imidazole nitrogen, enabling selective reactions elsewhere in a molecule.
Heterocyclic Chemistry
Serves as a valuable component in the synthesis of novel heterocyclic compounds. Its imidazole core is a prevalent motif in many biologically active molecules and materials.
Research and Development
Employed in academic and industrial research settings for the development of new chemical entities and synthetic methodologies. Its precise structure allows for controlled chemical transformations.
| Molecular weight | 196.36 |
|---|---|
| Empirical formula | C10H20N2Si |
| Assay | 97% |
| Boiling point | 250-260 °C(lit.) |
| Melting point | 31-35 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole used for?
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It is primarily used as a building block and intermediate in organic synthesis, particularly in the construction of complex heterocyclic molecules for research and development in pharmaceutical and fine chemical industries.
What is the CAS number and formula for this compound?
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The CAS number is 160425-48-9 and the empirical formula is C10H20N2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole with an assay of 97%. This product is intended for research and technical use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations?
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This compound is classified as a Warning with hazards including skin irritation (H315), eye irritation (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment such as eyeshields, gloves, and suitable respiratory protection should be used. Always consult the Safety Data Sheet (SDS) before handling.
How is this chemical shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole, adhering to international shipping and export regulations.
How can I request a sample or quote?
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To request a sample or a quote for 2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole, please contact our sales team through the website or by phone.
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