(S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine
(S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine (CAS 223121-01-5, C32H40FeP2) is a chiral ferrocenylphosphine ligand crucial for asymmetric synthesis. With a molecular weight of 542.45 g/mol, it facilitates highly enantioselective transformations, particularly in cross-coupling reactions. This ligand is a valuable tool for chemists developing stereoselective routes to complex molecules in pharmaceuticals and fine chemicals.
- IUPAC
- (1S)-1-[Bis(1,1-dimethylethyl)phosphino]-2-[(1S)-1-(diphenylphosphino)ethyl]ferrocene (acc to CAS),Josiphos SL-J502-2
![(S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine (C32H40FeP2) — chemical structure, CAS 223121-01-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F223121-01-5.png&w=3840&q=75)
Asymmetric Catalysis
This compound functions as a highly effective chiral ligand in transition metal-catalyzed asymmetric reactions, enabling the synthesis of enantiomerically enriched products.
Cross-Coupling Reactions
It is particularly useful in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig aminations, where it promotes high enantioselectivity.
Pharmaceutical Intermediate Synthesis
Its ability to control stereochemistry makes it invaluable for constructing chiral building blocks and intermediates in the synthesis of active pharmaceutical ingredients.
Fine Chemical Manufacturing
This ligand supports the development of stereoselective synthetic pathways for various fine chemicals, ensuring high optical purity in the final products.
| Molecular weight | 542.45 |
|---|---|
| Empirical formula | C32H40FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine used for?
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(S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine is primarily used as a chiral ligand in asymmetric synthesis, particularly in transition metal-catalyzed cross-coupling reactions to produce enantiomerically enriched compounds.
What are the CAS number and molecular formula?
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The CAS number is 223121-01-5, and the molecular formula is C32H40FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity (ee) of ≥99%. This product is not supplied as USP, BP, or EP grade.
How should this chemical be handled safely?
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When handling, wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Dispose of this material and its container in accordance with local regulations; it is classified under WGK Germany 3.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How are your chemicals packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for secure and compliant international shipment.
How can I request a sample or quote?
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Please contact our sales team directly via the website or by phone to request a sample or a quotation for (S)-1-[(RP)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine.
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