Amoxapine
Amoxapine (CAS: 14028-44-5) is a tricyclic antidepressant with the molecular formula C17H16ClN3O and a molecular weight of 313.78 g/mol. It functions as a biogenic amine reuptake inhibitor. Amoxapine is utilised in scientific research, particularly in neuroscience and cell biology, for investigating neurotransmission and related cellular processes. It is also classified as a bioactive small molecule.
- IUPAC
- 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine

Neuroscience Research
Amoxapine is employed in research settings to study neurotransmitter systems, particularly serotonin and norepinephrine reuptake inhibition. It serves as a tool for investigating mood disorders and related neurological pathways.
Cell Biology Studies
This compound is used in cell biology to explore cellular responses to neurotransmitter modulation. Its interactions with specific receptors and transporters make it valuable for understanding cell signalling.
Drug Discovery and Development
As an approved therapeutic and a bioactive small molecule, Amoxapine is a subject of interest in drug discovery. Researchers may use it as a reference compound or starting point for developing new therapeutic agents.
| Molecular weight | 313.78 |
|---|---|
| Empirical formula | C17H16ClN3O |
| Solubility | methanol: soluble |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR2A(3356), HTR2B(3357), HTR2C(3358) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Amoxapine used for?
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Amoxapine (CAS: 14028-44-5) is used in research for its properties as a biogenic amine reuptake inhibitor, particularly in neuroscience and cell biology studies investigating neurotransmission and cellular processes.
What are the CAS number and molecular formula for Amoxapine?
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The CAS number for Amoxapine is 14028-44-5, and its molecular formula is C17H16ClN3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Amoxapine as a research-grade chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety hazards associated with Amoxapine?
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Amoxapine is classified with the GHS07 symbol and a 'Warning' signal word. It carries the hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, faceshields, and gloves, should be used when handling this substance.
Is Amoxapine a controlled substance?
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The provided data does not indicate that Amoxapine is a controlled substance.
How is Amoxapine packed, shipped, and exported?
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Amoxapine is supplied in appropriate packaging for chemical reagents and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Amoxapine?
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To request a sample or a quote for Amoxapine, please contact the Tech Serve Solutions sales team through our website or by phone.
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