Ampicillin
Ampicillin (CAS: 69-53-4, C16H19N3O4S) is a broad-spectrum beta-lactam antibiotic with a molecular weight of 349.40 g/mol. It functions by inhibiting bacterial cell wall synthesis, making it effective against a range of Gram-positive and Gram-negative organisms. Primarily used in pharmaceutical research and development, Ampicillin serves as a crucial intermediate and reagent in the synthesis of various antibacterial agents and for microbiological applications. Stored at 2-8°C, it is supplied with an assay of ≥98.0%.
- IUPAC
- D-(−)-α-Aminobenzylpenicillin
- Synonyms
- D-(−)-α-Aminobenzylpenicillin

Antibacterial Agent Research
Ampicillin is extensively used in research laboratories to study bacterial resistance mechanisms and to develop new antibiotic therapies. Its known mechanism of action provides a baseline for comparative studies.
Pharmaceutical Intermediate
This compound serves as a key building block in the synthesis of other semi-synthetic penicillins and related pharmaceutical agents. Its chemical structure is integral to the development of advanced drug candidates.
Microbiological Applications
Ampicillin is employed as a selective agent in microbial cultures, particularly for genetic studies and the selection of transformed bacteria in molecular biology research. It helps in identifying and isolating specific microbial strains.
| Molecular weight | 349.40 |
|---|---|
| Empirical formula | C16H19N3O4S |
| Assay | ≥98.0% (NT) |
| Solubility | 1 M NH4OH: soluble50 mg/mL, clear, colorless |
| Optical activity | [α]20/D +295±5°, c = 0.2% in H2O |
| Storage temperature | 2-8°C |
| Impurities tested | ≤1% water |
| Melting point | 208 °C (dec.)(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ampicillin used for?
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Ampicillin is used in pharmaceutical research and development, as an intermediate in the synthesis of other antibacterial agents, and for microbiological applications, including selective agent in cultures.
What are the CAS number and formula for Ampicillin?
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The CAS number for Ampicillin is 69-53-4, and its empirical formula is C16H19N3O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ampicillin with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
What are the primary safety and handling precautions for Ampicillin?
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Ampicillin is classified as Danger, with hazards including skin and eye irritation, respiratory irritation, and potential for allergic skin reaction and serious respiratory tract irritation upon inhalation. Appropriate personal protective equipment, such as a dust mask (N95), eyeshields, face shields, and gloves, is essential during handling. Ensure good ventilation.
How is Ampicillin typically packed and exported by TSS?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe and compliant shipping. Specific packaging details are available upon request, tailored to the quantity and destination.
How can I request a sample or a quote for Ampicillin?
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To request a sample or a quote for Ampicillin, please contact our sales department through the website or directly via email or phone, providing your specific requirements.
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