Amrinone
Amrinone (CAS: 60719-84-8; C10H9N3O) is a cardiotonic agent. It functions as a phosphodiesterase inhibitor, increasing cyclic AMP levels to promote positive inotropy and vasodilation. Primarily utilised in research settings, it is employed in studies investigating cardiac function and related biochemical pathways. This compound is supplied by Tech Serve Solutions for laboratory and research purposes.
- IUPAC
- 5-Amino-(3,4′-bipyridin)-6(1H)-one,Inamrinone
- Synonyms
- 5-Amino-(3,4′-bipyridin)-6(1H)-one, Inamrinone
Cardiotonic Research
Amrinone is used in laboratory research to investigate its positive inotropic and vasodilatory effects on cardiac tissue. It serves as a tool for studying the mechanisms of phosphodiesterase inhibition and its impact on intracellular cyclic AMP signalling pathways.
Biochemical Investigations
This compound is utilised in biochemical studies to explore enzyme inhibition, specifically targeting phosphodiesterase enzymes. Researchers use it to understand enzyme kinetics and the modulation of second messenger systems.
Cell Biology Studies
Amrinone is applied in cell biology research to examine its effects on cellular processes, particularly those involving cyclic nucleotides and their regulation within various cell types.
| Molecular weight | 187.20 |
|---|---|
| Empirical formula | C10H9N3O |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 28-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Pde3a(50678) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Amrinone used for?
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Amrinone is primarily used in laboratory research as a cardiotonic agent and phosphodiesterase inhibitor to study cardiac function, cyclic AMP signalling, and enzyme inhibition pathways.
What are the CAS number and formula for Amrinone?
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Amrinone has the CAS number 60719-84-8 and the molecular formula C10H9N3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Amrinone for research purposes. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Amrinone be handled safely?
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Amrinone is classified as toxic if swallowed (H301). Handling requires strict safety precautions, including wearing appropriate personal protective equipment such as eyeshields, face shields, gloves, and using a P2 respirator cartridge. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Is Amrinone a controlled substance?
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The provided data does not indicate that Amrinone is a controlled substance. However, users should always comply with local regulations regarding chemical procurement and handling.
How is Amrinone packaged and shipped?
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Amrinone is packaged according to safety and regulatory standards for hazardous materials. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and customs regulations. Specific packaging details are available upon request.
How can I request a sample or quote for Amrinone?
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To request a sample or a quote for Amrinone, please contact our sales department through the website or by phone. Provide the product name and CAS number for prompt service.
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