(2R,2′R)-1,1′-Bis(6-methyl-2-pyridinylmethyl)-2,2′-bipyrrolidine tetrahydrochloride
(2R,2′R)-1,1′-Bis(6-methyl-2-pyridinylmethyl)-2,2′-bipyrrolidine tetrahydrochloride (CAS: 1228077-94-8) is a chiral ligand with a molecular weight of 496.34 g/mol. This compound serves as a crucial ligand for iron complexes, particularly noted for its application in the asymmetric olefin cis-dihydroxylation, achieving very high enantiomeric excess (ee). It is supplied by Tech Serve Solutions for advanced chemical synthesis and research.
- IUPAC
- (R,R)-6-Me2-BPBP tetrahydrochloride,2,2′-[(2R,2′R)-[2,2′-Bipyrrolidine]-1,1′-diylbis(methylene)]bis[6-methylpyridine] tetrahydrochloride
- Synonyms
- (R,R)-6-Me2-BPBP tetrahydrochloride2,2′-[(2R,2′R)-[2,2′-Bipyrrolidine]-1,1′-diylbis(methylene)]bis[6-methylpyridine] tetrahydrochloride2′-bipyrrolidine tetrahydrochloride
Asymmetric Olefin cis-Dihydroxylation
This compound functions as a highly effective ligand in iron-catalyzed asymmetric olefin cis-dihydroxylation reactions. It facilitates the synthesis of chiral diols with exceptional enantioselectivity, making it invaluable for stereoselective synthesis.
Chiral Ligand for Metal Catalysis
As a sophisticated chiral ligand, it is employed in asymmetric synthesis to control stereochemistry in catalytic transformations. Its structure enables precise coordination with metal centres, influencing the stereochemical outcome of reactions.
Intermediate in Fine Chemical Synthesis
This reagent is utilised in complex organic synthesis pathways, contributing to the construction of enantiomerically pure molecules for pharmaceutical and chemical research applications.
| Molecular weight | 496.34 |
|---|---|
| Empirical formula | C22H30N4 · 4HCl |
| Assay | ≥95.5% (HPLC)95.5-104.5% (AT)96% |
| Optical activity | [α]/D +10.0±1.0°, c = 1 in H2O |
| Application | Ligand for iron complexes - for the asymmetric olefin cis-dihydroxylation with very high ee1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,2′R)-1,1′-Bis(6-methyl-2-pyridinylmethyl)-2,2′-bipyrrolidine tetrahydrochloride used for?
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This compound is primarily used as a chiral ligand for iron complexes in asymmetric olefin cis-dihydroxylation reactions, achieving very high enantiomeric excess (ee).
What is the CAS number and formula for this compound?
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The CAS number is 1228077-94-8, and the empirical formula is C22H30N4 · 4HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥95.5% by HPLC and 95.5-104.5% by titration (AT), or 96% as stated. It is supplied as a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for this chemical?
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This compound is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315) and serious eye irritation (H319). Ensure appropriate personal protective equipment is worn, including gloves, eye protection, and protective clothing. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and documentation for the international shipment of this chemical in compliance with all relevant regulations.
How can I request a sample or quote for this product?
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To request a sample or a quote for (2R,2′R)-1,1′-Bis(6-methyl-2-pyridinylmethyl)-2,2′-bipyrrolidine tetrahydrochloride, please contact our sales team through the TSS website or by phone.
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