(2R,3R)-(−)-2,3-Butanediol
(2R,3R)-(−)-2,3-Butanediol (CAS 24347-58-8) is a chiral diol with a molecular weight of 90.12 g/mol. This C2-symmetric compound is a valuable building block and auxiliary in asymmetric synthesis. It is commonly employed in the creation of chiral ligands and is used to cyclocondense with ketones for NMR determination of optical purity. Available from Tech Serve Solutions.
- Synonyms
- 24347-58-8CH3CH(OH)CH(OH)CH3

Chiral Auxiliary in Asymmetric Synthesis
Serves as a versatile C2 symmetric chiral diol, enabling stereoselective transformations in organic synthesis. Its structure facilitates the creation of complex chiral molecules.
Building Block for Chiral Ligands
Acts as a fundamental component in the construction of chiral ligands. These ligands are crucial for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
NMR Determination of Optical Purity
Undergoes cyclocondensation with ketones to form derivatives that allow for the determination of optical purity using 13C NMR spectroscopy.
Organic Synthesis Intermediate
A useful chiral building block for the synthesis of various organic compounds where stereochemistry is critical.
| Molecular weight | 90.12 |
|---|---|
| Linear formula | CH3CH(OH)CH(OH)CH3 |
| Assay | 97% |
| Boiling point | 77.3-77.4 °C/10 mmHg(lit.) |
| Density | 0.987 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.433(lit.) |
| Optical activity | [α]23/D −13.2°, neat |
| Optical purity | ee: 99% (GLC) |
| Storage temperature | −20°C |
| Application | C2 symmetric chiral diol with versatile applications as a chiral auxiliary,1,2 building block,3,4,5 and chiral ligand.6,7 Cyclocondenses with ketones8 for 13C NMR determination of optical purity.9,10 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,3R)-(−)-2,3-Butanediol used for?
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(2R,3R)-(−)-2,3-Butanediol is primarily used as a chiral auxiliary and building block in asymmetric synthesis, for creating chiral ligands, and for determining optical purity via NMR spectroscopy.
What is the CAS number and formula for (2R,3R)-(−)-2,3-Butanediol?
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The CAS number is 24347-58-8, and the linear formula is CH3CH(OH)CH(OH)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R,3R)-(−)-2,3-Butanediol with an assay of 97% and an optical purity of ee: 99% (GLC). TSS does not represent this product as USP, BP, or EP grade.
How should (2R,3R)-(−)-2,3-Butanediol be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. It should be stored at -20°C. The flash point is 85°C (185°F).
Is (2R,3R)-(−)-2,3-Butanediol a controlled substance?
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Based on the provided data, there is no indication that (2R,3R)-(−)-2,3-Butanediol is a controlled substance.
How are chemicals from Tech Serve Solutions packed and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. Specific packing and shipping details are available upon request.
How can I request a quote or sample for (2R,3R)-(−)-2,3-Butanediol?
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Please contact the Tech Serve Solutions sales team directly to request a quote or a sample of (2R,3R)-(−)-2,3-Butanediol.
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