(2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane
(2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane (CAS 74839-84-2, C28H28P2) is a chiral diphosphine ligand. With a molecular weight of 426.47 g/mol, it is a crucial component in asymmetric synthesis. This compound facilitates enantioselective transformations, enabling the production of chiral molecules with high stereochemical control. Its utility is primarily recognised in academic research and industrial process development for creating stereospecific products, particularly in pharmaceuticals and fine chemicals.
- IUPAC
- (R,R)-Chiraphos
- Synonyms
- 74839-84-2C28H28P2(R,R)-Chiraphos

Asymmetric Catalysis
Serves as a chiral ligand in transition metal catalysis for enantioselective hydrogenation, allylic alkylation, and other asymmetric reactions. It plays a key role in synthesising chiral compounds with high optical purity.
Chiral Synthesis
Essential in the synthesis of enantiomerically pure pharmaceuticals, agrochemicals, and fine chemicals where specific stereoisomers are required for biological activity.
Ligand for Metal Complexes
Forms stable complexes with various transition metals, acting as a stereodirecting auxiliary in catalytic cycles. This is fundamental for developing novel catalytic systems.
| Molecular weight | 426.47 |
|---|---|
| Empirical formula | C28H28P2 |
| Melting point | 104-108 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane used for?
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It is primarily used as a chiral diphosphine ligand in asymmetric synthesis and catalysis, facilitating the enantioselective production of chiral molecules.
What is the CAS number and formula for (2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane?
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The CAS number is 74839-84-2, and the empirical formula is C28H28P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a typical assay meeting the specifications for research and development purposes. Please refer to the Certificate of Analysis for precise details. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should (2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane be handled safely?
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This compound is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust and ensure good ventilation. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
How is (2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane packed, shipped, and exported?
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The product is carefully packed to ensure stability and safety during transit, adhering to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for (2R,3R)-(+)-2,3-Bis(diphenylphosphino)butane?
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To request a sample or a detailed quote, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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