7-Methoxy-4-(trifluoromethyl)coumarin

CAS 575-04-2C11H7F3O3Biochemicals & Reagents

7-Methoxy-4-(trifluoromethyl)coumarin (CAS: 575-04-2, C11H7F3O3) is a fluorogenic coumarin derivative supplied by TSS. With a molecular weight of 244.17 g/mol, it is recognised for its fluorescent properties, making it valuable in biochemical research and as an enzyme substrate. Its primary applications lie in the development of sensitive detection assays and biochemical probes, leveraging its emission at 416 nm when excited at 333 nm in methanol.

IUPAC: Methyl 4-(trifluoromethyl)umbelliferyl ether

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7-Methoxy-4-(trifluoromethyl)coumarin (C11H7F3O3) — chemical structure, CAS 575-04-2; Life Science, fine chemical supplied by Tech Serve Solutions

ActivityBiochemicals and ReagentsEnzyme SubstratesEnzymesInhibitorsand SubstratesFluorogenicWavelength Index More...

01 /Applications

Enzyme Substrate

This compound serves as a fluorogenic substrate for various enzyme assays. Upon enzymatic cleavage, it releases a highly fluorescent product, enabling sensitive detection and quantification of enzyme activity in biological samples.

Biochemical Research Reagent

Utilised in biochemical and molecular biology research, 7-Methoxy-4-(trifluoromethyl)coumarin aids in the study of enzyme kinetics and cellular processes. Its fluorescent nature facilitates real-time monitoring in various experimental setups.

Fluorogenic Detection Systems

It is employed in the development of fluorogenic detection systems where a fluorescent signal is indicative of a specific biochemical event. The distinct excitation and emission wavelengths are advantageous for multiplexed assays.

02 /Properties

Molecular weight	244.17
Empirical formula	C11H7F3O3
Assay	≥99% (TLC)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

575-04-2

MDL number

MFCD00132980

PubChem substance

24900113

Beilstein registry

225039

05 /Additional specifications

Fluorescence	λex 333 nm; λem 416 nm in methanol

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 7-Methoxy-4-(trifluoromethyl)coumarin used for?

7-Methoxy-4-(trifluoromethyl)coumarin is primarily used as a fluorogenic enzyme substrate in biochemical research and for developing sensitive detection assays due to its fluorescent properties.

What are the CAS number and formula for 7-Methoxy-4-(trifluoromethyl)coumarin?

The CAS number is 575-04-2, and its empirical formula is C11H7F3O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of ≥99% by TLC. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.

What are the safety precautions for handling 7-Methoxy-4-(trifluoromethyl)coumarin?

This compound is a warning-level hazardous substance (GHS07). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask (N95), eye shields, and gloves. Ensure adequate ventilation and avoid dust formation.