7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-(2,4-dinitrophenyl)Lys amide
7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-(2,4-dinitrophenyl)Lys amide (CAS: 158584-09-9) is a specialised biochemical reagent with a molecular weight of 1675.84 g/mol. This fluorogenic substrate is primarily employed in biochemical research for the detection and quantification of specific enzyme activities. Its well-defined structure makes it a valuable tool for studying enzymatic processes, particularly those involving matrix metalloproteinases.
- Synonyms
- C78H110N22O20
Enzyme Activity Assays
Serves as a fluorogenic substrate for the characterisation and quantification of matrix metalloproteinases (MMPs), specifically MMP-3 and MMP-9. Its cleavage by these enzymes releases a fluorescent signal, enabling sensitive detection of enzyme activity in various biological samples.
Biochemical Research
A useful tool in biochemical and enzymatic research for understanding enzyme kinetics and mechanisms. Its specific peptide sequence and modifications allow for targeted studies of protease function and inhibition.
Drug Discovery Screening
Can be utilised in high-throughput screening (HTS) assays for identifying potential inhibitors of matrix metalloproteinases. Its fluorogenic nature allows for rapid and sensitive assessment of compound efficacy.
| Molecular weight | 1675.84 |
|---|---|
| Empirical formula | C78H110N22O20 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Application | Substrate for matrix metalloproteinases 3 and 9. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-(2,4-dinitrophenyl)Lys amide used for?
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This compound is used as a fluorogenic substrate for matrix metalloproteinases 3 and 9, enabling the study of their activity in biochemical research and drug discovery.
What are the CAS number and formula for this chemical?
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The CAS number is 158584-09-9. The empirical formula (Hill notation) is C78H110N22O20.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Store at -20°C.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How are your chemicals shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all relevant shipping regulations for international export.
How can I request a sample or quote?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quotation for this product.
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