4-(Trifluoromethoxy)iodobenzene
4-(Trifluoromethoxy)iodobenzene (CAS: 103962-05-6), with the molecular formula IC6H4OCF3 and a molecular weight of 288.01 g/mol, is a valuable organic building block. This halogenated aromatic ether features a trifluoromethoxy group, making it a useful intermediate in organic synthesis. It is primarily employed in the development of novel compounds within the pharmaceutical and agrochemical industries.
- IUPAC
- 1-Iodo-4-trifluoromethoxybenzene,4-Iodo-α,α,α-trifluoromethoxybenzene
- Synonyms
- 1-Iodo-4-trifluoromethoxybenzene4-Iodo-α,α,α-trifluoromethoxybenzene
Organic Synthesis Intermediate
This compound serves as a versatile building block in the synthesis of more complex organic molecules. Its iodobenzene moiety readily participates in cross-coupling reactions, while the trifluoromethoxy group can impart unique electronic and lipophilic properties to target structures.
Pharmaceutical Research
4-(Trifluoromethoxy)iodobenzene is utilised in the discovery and development of new pharmaceutical agents. The trifluoromethoxy substituent is often incorporated to enhance metabolic stability, bioavailability, or receptor binding affinity of drug candidates.
Agrochemical Development
In the agrochemical sector, this compound acts as a key intermediate for the synthesis of novel pesticides, herbicides, and fungicides. The unique properties conferred by the trifluoromethoxy group can lead to improved efficacy and environmental profiles of crop protection agents.
| Molecular weight | 288.01 |
|---|---|
| Linear formula | IC6H4OCF3 |
| Assay | 97% |
| Boiling point | 177-179 °C(lit.) |
| Density | 1.84 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)iodobenzene used for?
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4-(Trifluoromethoxy)iodobenzene is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical and agrochemical compounds.
What is the CAS number and chemical formula for 4-(Trifluoromethoxy)iodobenzene?
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The CAS number is 103962-05-6 and the chemical formula is IC6H4OCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)iodobenzene with an assay of 97%. This product is typically considered a research or technical grade material and is not represented as USP, BP, or EP grade.
What are the primary safety hazards associated with 4-(Trifluoromethoxy)iodobenzene?
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This compound is classified with GHS07 and the signal word Warning, indicating it can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used.
How is 4-(Trifluoromethoxy)iodobenzene packed, shipped, and exported?
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4-(Trifluoromethoxy)iodobenzene is carefully packed according to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for 4-(Trifluoromethoxy)iodobenzene?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing your specific requirements.
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