4-(Trifluoromethoxy)benzyl bromide
4-(Trifluoromethoxy)benzyl bromide (CAS: 50824-05-0) is a halogenated aromatic compound with the molecular formula CF3OC6H4CH2Br and a molecular weight of 255.03 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the preparation of more complex molecules containing the trifluoromethoxybenzyl moiety. It is frequently employed in the development of pharmaceuticals and agrochemicals, acting as an intermediate in multi-step synthetic pathways.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of diverse organic compounds. Its reactive benzyl bromide group allows for facile nucleophilic substitution reactions, enabling the introduction of the 4-(trifluoromethoxy)benzyl group into target molecules.
Pharmaceutical Research
Applied in the development of novel pharmaceutical agents. The trifluoromethoxy group can impart desirable pharmacokinetic properties, such as increased lipophilicity and metabolic stability, making it a sought-after structural element in drug discovery.
Agrochemical Development
Serves as a precursor in the synthesis of agrochemicals, including pesticides and herbicides. Its incorporation into active ingredients can enhance efficacy and modify the biological activity profile of crop protection agents.
Material Science
Potential applications in material science for the synthesis of specialised polymers or functional materials where the unique electronic properties of the trifluoromethoxy group are desired.
| Molecular weight | 255.03 |
|---|---|
| Linear formula | CF3OC6H4CH2Br |
| Assay | 97% |
| Boiling point | 82-84 °C/10 mmHg(lit.) |
| Density | 1.594 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.48(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 94 °C / 201.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)benzyl bromide primarily used for?
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4-(Trifluoromethoxy)benzyl bromide is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 4-(Trifluoromethoxy)benzyl bromide?
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The CAS number is 50824-05-0, and the chemical formula is CF3OC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent it as USP, EP, or BP grade.
How should 4-(Trifluoromethoxy)benzyl bromide be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with extreme caution, wearing appropriate personal protective equipment including face shields, gloves, goggles, and suitable respiratory protection. Ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
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As per the provided safety data, this chemical is classified under UN 3265, 8 / PGII, indicating it is a corrosive liquid, acidic, organic, n.o.s. Packaging and export adhere to strict international regulations for hazardous materials.
How can I request a quote or sample for 4-(Trifluoromethoxy)benzyl bromide?
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Please contact our sales team directly via the website or phone to request a quotation or to arrange for a product sample.
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