Terbinafine hydrochloride

CAS 78628-80-5C21H25N · HClBiochemicals & Reagents

Terbinafine hydrochloride (CAS: 78628-80-5; Formula: C21H25N · HCl; MW: 327.89) is a synthetic allylamine antifungal agent. It is primarily recognised for its efficacy in treating superficial dermatophyte infections, including those affecting the toenails and fingernails, as well as common conditions like ringworm and jock itch. This compound also finds application in various laboratory research settings, particularly in adsorption, partition, and stability studies.

IUPAC: trans-N-(6,6-Dimethyl-2-hepten-4-ylyl)-N-methyl-1-naphthylmethylamine hydrochloride

Email us

Terbinafine hydrochloride (C21H25N · HCl) — chemical structure, CAS 78628-80-5; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics T-ZAntifungalAntimycobacterialBiochemicals and ReagentsEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitors

01 /Applications

Treatment of Dermatophyte Infections

Terbinafine hydrochloride is a potent antifungal agent used to treat onychomycosis (fungal nail infections) and other superficial mycoses such as tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm).

Adsorption and Partition Studies

This compound is utilised in scientific research for studies involving adsorption and partition phenomena. Its properties make it a useful model compound for understanding these processes in various matrices.

Stability Investigations

Terbinafine hydrochloride serves as a subject in stability studies, allowing researchers to investigate its degradation pathways and shelf-life under different conditions, crucial for formulation development and quality control.

02 /Properties

Molecular weight	327.89
Empirical formula	C21H25N · HCl
Assay	≥98%
Application	Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch1. It is used in adsorption, partition and stability studies2,3.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H410Very toxic to aquatic life with long-lasting effects

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P273Avoid release to the environment
P305IF IN EYES
P501Dispose of contents and container per local regulations

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi,N
Risk statements (R)	36/37/38-50/53
Safety statements (S)	26-60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

78628-80-5

MDL number

MFCD00145430

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Terbinafine hydrochloride used for?

Terbinafine hydrochloride is used to treat fungal infections such as ringworm, jock itch, and nail infections. It is also employed in laboratory studies related to adsorption, partition, and stability.

What are the CAS number and formula for Terbinafine hydrochloride?

The CAS number for Terbinafine hydrochloride is 78628-80-5, and its formula is C21H25N · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Terbinafine hydrochloride with an assay of ≥98%. This product is not classified as USP, BP, or EP grade unless explicitly stated otherwise, and TSS does not represent it as such.

How should Terbinafine hydrochloride be handled safely?

Terbinafine hydrochloride is classified with GHS07 and GHS09 symbols, indicating it can cause skin and eye irritation and is toxic to aquatic life with long-lasting effects. Handling requires a dust mask (type N95 US), eyeshields, and gloves. Avoid release to the environment. In case of contact, rinse cautiously with water. Refer to the Safety Data Sheet for full handling instructions.

Is Terbinafine hydrochloride a controlled substance?

The provided data does not indicate that Terbinafine hydrochloride is a controlled substance.

How is Terbinafine hydrochloride packed and exported?

Terbinafine hydrochloride is packed and exported in compliance with relevant regulations, including UN 3077 specifications for environmentally hazardous substances. Specific packaging details are available upon request.

How can I request a sample or quote for Terbinafine hydrochloride?

To request a sample or a quote for Terbinafine hydrochloride, please contact our sales team through the TSS website or by phone, providing your specific requirements.