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Phalloidin from Amanita phalloides

CAS 17466-45-4C35H48N8O11SCell Biology

Phalloidin from Amanita phalloides (CAS: 17466-45-4) is a cyclic heptapeptide toxin. Its empirical formula is C35H48N8O11S with a molecular weight of 788.87 g/mol. This bioactive molecule is primarily utilised as a critical tool in cell biology for studying actin dynamics and as a probe for imaging cellular structures. It is widely employed in microscopy for tracking cellular processes and verifying cytoskeletal organisation.

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Phalloidin from Amanita phalloides (C35H48N8O11S) — chemical structure, CAS 17466-45-4; Life Science, fine chemical supplied by Tech Serve Solutions
Actin Inhibitors and ProbesBioactive Small MoleculesCell BiologyGeneral Stem Cell BiologyMushroomStains/DyesStem Cell BiologyStem Cell CharacterizationStem Ce
01 /Applications

Actin Staining and Visualization

Phalloidin binds with high affinity to F-actin filaments, making it an indispensable probe for visualising the actin cytoskeleton in fixed and permeabilised cells. Its specificity allows for detailed studies of cell shape, motility, and intracellular transport.

Cellular Research and Diagnostics

Used in various cell biology research applications, including studying cell division, migration, and development. It serves as a vital reagent for understanding cellular mechanics and signalling pathways.

In Vivo/In Vitro Stem Cell Tracking

Phalloidin is applied for tracking stem cell behaviour and differentiation processes. Its ability to highlight cytoskeletal changes aids in characterising stem cell populations and their responses to stimuli.

Biochemical Assays

Utilised in biochemical assays to quantify or study actin polymerisation and depolymerisation dynamics. This helps in the characterisation of actin-binding proteins and drug screening.

02 /Properties
Molecular weight788.87
Empirical formulaC35H48N8O11S
Assay≥90%
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H300Fatal if swallowed

Precautionary statements

  • P260Do not breathe dust, fume, gas, mist, vapours or spray
  • P264Wash thoroughly after handling
  • P280Wear protective gloves, clothing and eye/face protection
  • P284Wear respiratory protection
  • P301IF SWALLOWED
  • P302IF ON SKIN
Transport (UN / ADR)UN 3462 6.1 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)T+
Risk statements (R)26/27/28
Safety statements (S)22-28-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
17466-45-4
MDL number
MFCD03427567
PubChem substance
24898277
Beilstein registry
4347460
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Phalloidin from Amanita phalloides used for?

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Phalloidin from Amanita phalloides is primarily used as a probe for visualising and studying the actin cytoskeleton in cell biology research, including stem cell tracking and biochemical assays.

What are the CAS number and chemical formula for Phalloidin from Amanita phalloides?

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The CAS number is 17466-45-4 and the empirical formula is C35H48N8O11S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Phalloidin from Amanita phalloides with an assay of ≥90%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling Phalloidin?

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Phalloidin is highly toxic and can be fatal if swallowed, in contact with skin, or if inhaled (H300 +H310 + H330). Handle with extreme caution in a well-ventilated area or fume hood, using appropriate personal protective equipment including gloves, lab coat, and eye protection. Refer to the Safety Data Sheet for detailed handling procedures.

How is Phalloidin from Amanita phalloides packed, shipped, and exported?

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Phalloidin is packed and shipped according to strict international regulations for hazardous materials. Tech Serve Solutions is experienced in exporting chemicals globally, ensuring compliance with all relevant transport and customs requirements.

How can I request a sample or quote for Phalloidin from Amanita phalloides?

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To request a sample or a quotation, please contact our sales team through the website or by phone. Please provide your contact details and the required quantity.

Need Phalloidin from Amanita phalloides in a specific grade or volume?