Pentoxifylline
Pentoxifylline (CAS: 6493-05-6, Formula: C13H18N4O3) is a xanthine derivative with a molecular weight of 278.31 g/mol. This white solid compound is known for its phosphodiesterase inhibitory activity, which leads to increased intracellular cyclic AMP levels. It has been utilised for its rheological properties, improving blood flow by increasing erythrocyte flexibility and decreasing blood viscosity. Pentoxifylline is primarily recognised as an approved therapeutic agent.
- IUPAC
- 3,7-Dimethyl-1-(5-oxohexyl)xanthine,Trental
- Synonyms
- 3,7-Dimethyl-1-(5-oxohexyl)xanthineTrental
Rheological Agent
Pentoxifylline is used to improve blood flow characteristics. It enhances erythrocyte deformability and reduces blood viscosity, making it valuable in circulatory support applications.
Phosphodiesterase Inhibitor
As a phosphodiesterase inhibitor, this compound increases cyclic AMP levels within cells. This mechanism is fundamental to its biological activities and therapeutic effects.
Research Chemical
Pentoxifylline serves as a research tool in studies investigating cell signaling pathways, G proteins, and cyclic nucleotide metabolism. Its well-defined mechanism of action makes it useful for cellular biology research.
| Molecular weight | 278.31 |
|---|---|
| Empirical formula | C13H18N4O3 |
| Form | solid |
| Colour | white |
| Solubility | H2O: ≥43 mg/mL |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA2B(136), LITAF(9516), PDE4B(5142), TNF(7124)rat ... Tnf(24835) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentoxifylline used for?
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Pentoxifylline is primarily used as an approved therapeutic agent to improve blood flow by enhancing erythrocyte flexibility and reducing blood viscosity. It also acts as a phosphodiesterase inhibitor, making it useful in various research applications.
What are the CAS number and formula for Pentoxifylline?
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The CAS number for Pentoxifylline is 6493-05-6, and its molecular formula is C13H18N4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pentoxifylline with a purity typically greater than or equal to 98%. While used as an approved therapeutic agent, TSS does not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the safety and handling considerations for Pentoxifylline?
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Pentoxifylline is classified as harmful if swallowed (H302) and requires handling with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. It is also labelled with the GHS07 symbol and a 'Warning' signal word.
How is Pentoxifylline packed, shipped, and exported?
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Pentoxifylline is typically supplied as a white solid and is carefully packed to ensure safe transit. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Pentoxifylline?
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To request a sample or a quotation for Pentoxifylline, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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