Pentylenetetrazole
Pentylenetetrazole (CAS 54-95-5), with the molecular formula C6H10N4 and a molecular weight of 138.17 g/mol, is a nitrogenous heterocyclic compound. It is known for its stimulant properties, primarily affecting the central nervous system. Pentylenetetrazole is widely employed in neuroscientific research as a tool for inducing seizures in animal models to study epilepsy and investigate anticonvulsant drugs. It is also utilised in biochemical assays.
- IUPAC
- α,β-Cyclopentamethylenetetrazole,1,5-Pentamethylenetetrazole,6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine,Metrazole
- Synonyms
- MetrazolePentetrazole1,5-Pentamethylenetetrazole6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine
Neuroscience Research Tool
Pentylenetetrazole is a standard reagent for inducing generalized convulsions in laboratory animals. This makes it invaluable for studying the mechanisms of epilepsy, testing the efficacy of antiepileptic drugs, and exploring neuroprotective strategies.
Pharmacological Studies
As a known convulsant and CNS stimulant, Pentylenetetrazole serves as a probe in pharmacological research to understand neurotransmitter systems and drug interactions within the central nervous system.
Biochemical Assays
The compound can be used in various biochemical investigations, particularly those involving ion channels or neuronal excitability, providing a means to modulate cellular activity.
| Molecular weight | 138.17 |
|---|---|
| Empirical formula | C6H10N4 |
| Boiling point | 194 °C/12 mmHg(lit.) |
| Storage temperature | −20°C |
| Melting point | 59-61 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentylenetetrazole primarily used for?
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Pentylenetetrazole (CAS 54-95-5) is primarily used as a research tool in neuroscience to induce seizures in animal models for studying epilepsy and testing anticonvulsant drugs. It also finds application in pharmacological and biochemical studies.
What are the CAS number and molecular formula for Pentylenetetrazole?
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The CAS number for Pentylenetetrazole is 54-95-5, and its molecular formula is C6H10N4.
What grade and purity does Tech Serve Solutions supply for Pentylenetetrazole?
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Tech Serve Solutions typically supplies Pentylenetetrazole in research grades. Please refer to the product's Certificate of Analysis for specific assay and purity details. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Pentylenetetrazole be handled safely?
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Pentylenetetrazole is a toxic substance that causes skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Pentylenetetrazole a controlled substance?
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Based on the provided data, Pentylenetetrazole is classified as toxic and a dangerous substance (UN 2811, Hazard Class 6.1). It is not explicitly listed as a scheduled or controlled substance in this data, but users should verify local regulations.
How is Pentylenetetrazole packed and shipped?
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Pentylenetetrazole is packed according to international transport regulations for hazardous materials, being classified under UN 2811, Class 6.1, Packing Group III. Tech Serve Solutions exports globally, adhering to all relevant shipping requirements.
How can I request a sample or quote for Pentylenetetrazole?
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To request a sample or a quote for Pentylenetetrazole, please contact the Tech Serve Solutions sales team through our website or by phone. Provide your specific requirements and delivery details.
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