Phaclofen

CAS 114012-12-3C9H13ClNO3PCell Biology

Phaclofen (CAS: 114012-12-3; Empirical Formula: C9H13ClNO3P; Molar Mass: 249.63 g/mol) is a chemical compound identified as an antagonist. It is primarily used in research settings for its specific biological activity, particularly within the fields of neuroscience and cell biology. Phaclofen serves as a valuable tool for investigating GABAergic neurotransmission and related cellular signaling pathways.

IUPAC: 3-Amino-2-(4-chlorophenyl)propanephosphonic acid

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Phaclofen (C9H13ClNO3P) — chemical structure, CAS 114012-12-3; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesCell BiologyGABAergicsNeuroscienceNeurotransmissionNeurotransmittersP More...

01 /Applications

Neuroscience Research

Phaclofen is employed as a pharmacological tool to study the function of GABA receptors in the central nervous system. Its antagonistic properties aid in dissecting neuronal pathways and understanding neurotransmitter roles.

Cell Biology Investigations

This compound is utilised in cell-based assays to explore cellular responses mediated by GABAergic signaling. It helps researchers elucidate intracellular mechanisms and receptor-ligand interactions.

Bioactive Small Molecule Studies

As a bioactive small molecule, Phaclofen is used in screening and validation studies to identify and characterise biological targets. Its known activity provides a benchmark for new compound discovery.

02 /Properties

Molecular weight	249.63
Empirical formula	C9H13ClNO3P
Form	solid
Colour	white
Solubility	0.1 M HCl: soluble13.3 mg/mLmethanol: soluble19.3 mg/mLDMSO: insoluble
Impurities tested	≥97% (NMR)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

114012-12-3

MDL number

MFCD00069328

05 /Additional specifications

Gene Information	human ... GABBR1(2550), GABBR2(9568)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Phaclofen used for?

Phaclofen is used in research for studying GABAergic neurotransmission, cell signaling, and as a tool in neuroscience and cell biology investigations. It acts as an antagonist.

What is the CAS number and chemical formula for Phaclofen?

The CAS number for Phaclofen is 114012-12-3, and its empirical formula is C9H13ClNO3P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Phaclofen with a purity of ≥97% (NMR). This product is intended for research purposes and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.

How should Phaclofen be handled safely?

Phaclofen is a warning-hazard substance (GHS07). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Ensure adequate ventilation (H315-H319-H335).

Is Phaclofen a controlled substance?

The provided data does not indicate that Phaclofen is a controlled substance.

How is Phaclofen packed and exported?

Phaclofen is supplied as a white solid. Specific packaging details for export are available upon request and comply with international shipping regulations for chemical substances.

How can I request a sample or quote for Phaclofen?

To request a sample or quote for Phaclofen, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels, referencing the product CAS number 114012-12-3.