Telmisartan

CAS 144701-48-4C33H30N4O2Biochemicals & Reagents

Telmisartan (CAS 144701-48-4), a complex organic molecule with the formula C33H30N4O2, is a research chemical with a molecular weight of 514.62 g/mol. It functions as an angiotensin II receptor antagonist. This compound has been utilised in preclinical studies investigating its effects on myocardial infarction models, kidney cortex responses, and colorectal cancer growth, serving as a valuable tool in cardiovascular and oncological research.

IUPAC: 4′[(1,4′-Dimethyl-2′-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl][1,1′-biphenyl]-2-carboxylic acid,BIBR 277
Synonyms: BIBR 2774′[(1,4′-Dimethyl-2′-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl][1,1′-biphenyl]-2-carboxylic acid

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Telmisartan (C33H30N4O2) — chemical structure, CAS 144701-48-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsBoehringer IngelheimCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscienceNeurotransmissionNeurotransmitter Receptors

01 /Applications

Cardiovascular Research

Telmisartan has been employed in studies examining its role in myocardial infarction models. It has been used to investigate its effects on the upregulation of CCN1 and reduction of CCN2 levels in atrial cardiomyocytes.

Renal Studies

The compound has been utilised to evaluate its impact on the expression of CCN1 within the kidney cortex of mice subjected to myocardial infarction, aiding research into renal responses to cardiac events.

Oncology Research

Telmisartan has been investigated for its potential efficacy against tumor growth in preclinical models of colorectal cancer, offering a potential avenue for research in cancer therapeutics.

02 /Properties

Molecular weight	514.62
Empirical formula	C33H30N4O2
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: >5 mg/mL at 60 °CH2O: insoluble
Application	Telmisartan has been used as an AT1 receptor antagonist to study its effects on mouse models of myocardial infarction. This study reported that telmisartan inhibited the CCN1 upregulation and reduced CCN2 levels atrial cardiomyocytes1. Telmisartan has also been used to evaluate its effect on the expression of CCN1 in kidney cortex of mice subjected to myocardial infarction2. Furthermore, telmisartan has been used to test its efficacy against tumor growth in mouse models of colorectal cancer3.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

144701-48-4

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Telmisartan used for?

Telmisartan is primarily used as a research chemical. It has been utilised in preclinical studies to investigate its effects on myocardial infarction models, kidney cortex responses, and colorectal cancer growth, and acts as an AT1 receptor antagonist.

What is the CAS number and molecular formula for Telmisartan?

The CAS number for Telmisartan is 144701-48-4, and its molecular formula is C33H30N4O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Telmisartan with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Telmisartan be handled?

When handling Telmisartan, it is recommended to use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with WGK Germany 2.

How is Telmisartan packaged and shipped?

Telmisartan is typically supplied as a white solid. For detailed information on packaging, shipping, and export capabilities, please contact our sales team.