4-(Trifluoromethoxy)benzoic acid
4-(Trifluoromethoxy)benzoic acid (CAS: 330-12-1), with the molecular formula CF3OC6H4CO2H and a molar mass of 206.12 g/mol, is a valuable organic building block. This carboxylic acid derivative features a trifluoromethoxy group, imparting unique electronic properties. It is primarily utilised in chemical synthesis and research, serving as an intermediate for creating more complex molecules. Its reactive carboxylic acid moiety allows for diverse derivatisation, making it a versatile compound in organic chemistry.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of various organic compounds. The presence of the trifluoromethoxy group can influence the properties of the final products.
Research and Development
Widely employed in academic and industrial research laboratories for exploring new chemical pathways and developing novel materials or pharmaceuticals.
Building Block for Complex Molecules
Its structure makes it suitable for incorporation into larger molecular frameworks, potentially for applications in medicinal chemistry or materials science.
| Molecular weight | 206.12 |
|---|---|
| Linear formula | CF3OC6H4CO2H |
| Assay | 96% |
| Melting point | 150-154 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)benzoic acid used for?
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4-(Trifluoromethoxy)benzoic acid (CAS: 330-12-1) is used as a building block and intermediate in organic synthesis and chemical research and development.
What is the CAS number and molecular formula for 4-(Trifluoromethoxy)benzoic acid?
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The CAS number is 330-12-1 and the molecular formula is CF3OC6H4CO2H.
What grade and purity does Tech Serve Solutions supply for 4-(Trifluoromethoxy)benzoic acid?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)benzoic acid with an assay of 96%. This product is not guaranteed to be USP, BP, EP or pharmaceutical grade.
How should 4-(Trifluoromethoxy)benzoic acid be handled safely?
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This compound can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including eyeshields, gloves, and a dust mask (type N95 US) should be used. Ensure good ventilation.
How is 4-(Trifluoromethoxy)benzoic acid packed and shipped by TSS?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging and compliance with international shipping regulations.
How can I request a sample or quote for 4-(Trifluoromethoxy)benzoic acid?
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You can request a sample or quote for 4-(Trifluoromethoxy)benzoic acid by contacting our sales team through the website or by calling us directly.
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