Butyl(chloro)dimethylsilane
Butyl(chloro)dimethylsilane (CAS: 1000-50-6), with the molecular formula C6H15ClSi and a molecular weight of 150.72 g/mol, is a versatile organosilicon compound. It serves as a valuable intermediate and reagent in chemical synthesis, particularly in applications involving protection and derivatization strategies. Its reactive nature makes it useful for introducing the butyldimethylsilyl group into various organic molecules.
- IUPAC
- Butyldimethylchlorosilane,Butyldimethylsilyl chloride

Protecting Group Chemistry
Butyl(chloro)dimethylsilane is employed as a reagent for the protection of hydroxyl and other functional groups. It facilitates the formation of stable silyl ethers, which can be selectively removed later in a synthetic sequence.
Organic Synthesis Intermediate
This chlorosilane acts as a key building block in the synthesis of more complex organosilicon compounds. Its reactivity allows for further functionalization and incorporation into diverse molecular architectures.
Derivatization Reagent
It can be used to derivatize molecules for analytical purposes, such as gas chromatography, by increasing volatility and thermal stability of analytes.
| Molecular weight | 150.72 |
|---|---|
| Linear formula | CH3(CH2)3Si(CH3)2Cl |
| Assay | 98% |
| Boiling point | 138 °C/752 mmHg(lit.) |
| Density | 0.868 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.418(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 2985 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butyl(chloro)dimethylsilane used for?
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Butyl(chloro)dimethylsilane is primarily used in chemical synthesis as a reagent for protecting and derivatizing functional groups, particularly in the preparation of organosilicon compounds.
What is the CAS number and formula for Butyl(chloro)dimethylsilane?
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The CAS number is 1000-50-6, and its molecular formula is CH3(CH2)3Si(CH3)2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Butyl(chloro)dimethylsilane with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Butyl(chloro)dimethylsilane be handled safely?
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Butyl(chloro)dimethylsilane is a highly flammable liquid and vapor and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, goggles, and face shields, in a well-ventilated area, and keep away from heat and open flames.
How is Butyl(chloro)dimethylsilane packed and shipped?
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Butyl(chloro)dimethylsilane is shipped as UN 2985, Hazard Class 8(3), Packing Group II, indicating it is a corrosive and flammable liquid requiring specialized handling and transport.
How can I request a quote or sample?
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Please contact our sales team via the website or directly to request a quote or sample of Butyl(chloro)dimethylsilane.
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